9780781718608

George Washington Univ., Washington, D.C. Text on evaluating medical literature in terms of validity and value. Previous edition: c1996. For students and practitioners. CD-ROM contains self-assessment questions and includes available CME credit hours. NOTE: Approval items which include software can be returned if desired after viewing. Softcover. Added to Brandon-Hill Medical List in April 2001.

Preface

vii

Acknowledgments

ix

I. Studying a Study

Introduction and Sample Test

3

(2)

Uniform Frameworks

5

(8)

Study Design

13

(3)

Assignment

16

(5)

Assessment

21

(5)

Analysis

26

(16)

Interpretation

42

(7)

Extrapolation

49

(8)

Randomized Clinical Trials

57

(19)

Database Research: Nonconcurrent Cohort Studies

76

(9)

Meta-Analysis

85

(15)

Studying a Study: Questions to Ask and Flaw-Catching Exercises

100

(27)

II. Testing a Test

Introduction to Testing a Test

127

(3)

Variability of the Test

130

(3)

Reference Interval

133

(9)

Defining Disease: The Gold Standard

142

(2)

Diagnostic Performance of Tests

144

(9)

Comparing Tests

153

(5)

Screening

158

(8)

Testing a Test: Questions to Ask and Flaw-Catching Exercises

166

(13)

III. Rating a Rate

Introduction to Rates

179

(5)

Sampling of Rates

184

(4)

Standardization of Rates

188

(6)

Sources of Differences in Rates

194

(6)

Putting It Together: Measuring Life Expectancy

200

(6)

Rating a Rate: Questions to Ask and Flaw-Catching Exercises

206

(11)

IV. Considering Costs and Evaluating Effectiveness

Introduction and Study Design of Decision-Making Investigations

217

(10)

Assignment

227

(8)

Assessment

235

(5)

Analysis

240

(9)

Interpretation

249

(7)

Extrapolation

256

(6)

Decision-Making Investigations: Questions to Ask and Flaw-Catching Exercises

262

(13)

V. Selecting a Statistic

Basic Principles

275

(10)

Univariable Analyses

285

(7)

Bivariable Analyses

292

(9)

Multivariable Analyses

301

(12)

Flowchart Summary

313

(8)

Glossary

321

(22)

Subject Index

343

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Studying a Study and Testing a Test : How to Read the Health Science Literature

Studying a Study and Testing a Test : How to Read the Health Science Literature

0781718600

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Table of Contents

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