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Radiation safety and risk management, a critical issue in the nuclear age, is an ongoing concern in the field of radiation health risk sciences. It is the particular mission and task of the Nagasaki University Global COE program to explore human health risks from radiation on a global scale and to come up with measures for overcoming its negative legacies. Ionizing radiation is a well-documented human cancer risk factor, and long-term health consequences in individuals exposed at a young age to such events as the Hiroshima and Nagasaki atomic bombing are now being followed up. Unique and comprehensive, this book introduces updated radiation health-related issues, including the proper collection and analysis of biological samples, cancer research, psychological effects, fair disclosure, and the effects of low-dose exposure as they apply to future public health policy. Also addressed is the need for emergency radiation medicine in case of accidents.
Table of Contents
Overview of the Global COE ProgramGlobal Strategic Center for Radiation Health Risk ControlOverview of the LecturesDiscussion on Points of Radiation Safety and the Scope of The University of Tokyo Global COE ProgramNetwork System for Radiation Emergency Medicine in Japan and the Role of Hiroshima UniversityNon-DNA-Targeted Effects and Low-Dose Radiation Risk Update from the Chernobyl Tissue Bank: Effect of Latency on Different Types of Thyroid Cancer Post-ChernobylCurrent Risk Estimate of Radiation-Related Cancer and Our Insight into the Future Atomic Bomb Disease MedicineIntroduction of Atomic Bomb Disease Medical Research in Global COE ProgramThe Offspring of Atomic Bomb Survivors: Cancer and Non-Cancer Mortality and Cancer IncidenceIschemic Heart Disease Among Atomic Bomb Survivors: Possible Mechanism(s) Linking Ischemic Heart Disease and Radiation Exposure Leukemia, Lymphoma, and Multiple Myeloma Incidence in the LSS Cohort: 1950?2001Follow-Up Study of 78 Healthy Exposed Atomic Bomb Survivors for 35 Years in Hiroshima, with Special Reference to Multiple CancersInternational Radiation Health Sciences Research Activities and Projects Within a Framework of International Radiation Health Sciences ResearchAge and Prognosis: Do Adjuvant Therapies Influence the Real Prognosis?Mortality of the Chernobyl Emergency Workers: Analysis of Dose Response by Cohort Studies Covering Follow-Up Period of 1992?2006Twenty Years After Chernobyl: Implications for Radiation Health Risk ControlFallout Exposure of the Population and Thyroid Nodular DiseasesRadiation Basic Life Sciences, Part 1Higher-Order Chromatin Structure and Nontargeted Effects p53 Dependency of Delayed and Untargeted Recombination in Mouse Embryos Fertilized by Irradiated SpermThe Yin and Yang of Low-Dose RadiobiologyInduction and Persistence of Cytogenetic Damage in Mouse Splenocytes Following Whole-Body X-Irradiation Analysed by Fluorescence In Situ Hybridisation. V. Heterogeneity/Chromosome SpecificityCancer ResearchMolecular Understanding of RET/PTC-Mediated Thyroid CarcinogenesisMolecular Prediction of Therapeutic Response and Adverse Effect of Chemotherapy in Breast CancerMultiple Roles of NBS1 for Genotoxic and Nongenotoxic StressesRadiation Basic Life Sciences, Part 2The DNA Damage Response in Nontargeted CellsThe Role of Telomere Dysfunction in Driving Genomic InstabilitySecretory Clusterin Is a Marker of Tumor Progression Regulated by IGF-1 and Wnt Signaling PathwaysTarget of Radiation Carcinogenesis Is Protein: Becoming Triploid Is Proximate Cause of Cell TransformationAdult Stem Cells, the Barker Hypothesis, Epigenetic Events, and Low-Level Radiation EffectsCombined Effect of Ionizing Radiation and N-Ethyl-N-Nitrosourea on Mutation Induction and Lymphoma Developmentg-Ray-Induced Mouse Thymic Lymphomas: Bcl11b Inactivation and Prelymphoma CellsRadiation Risk ManagementFramework of Radiation Safety Management in Japan: Laws, Administrative Agencies, and Supporting AssociationsBackground Radiation Dose to the Population Around the Kudankulam Nuclear Power PlantInternational Cooperation in Radiation Emergency Medical Preparedness: Establishment of a Medical Network in AsiaDisaster and Mental HealthLong-Term Biopsychosocial Consequences of Disaster: Focuson Atomic Bomb SurvivorsHealth Status of Children Exposed to the Chernobyl Accident In Utero: Observations in 1989?2003 and the Implications for Prioritizing Prophylactic ProgramsPsychological Consequences More Than Half a Century After the Nagasaki Atomic BombingRadiation and CancerSignificance of Oncogene Amplifications in Breast Cancer in Atomic Bomb Survivors: Associations with Radiation Exposure and Histological GradeParacrine Interactions Between Normal, but Not Cancer, Epithelial and Normal Mesenchymal Cells Attenuate Radiation-Induced DNA DamageChernobyl and Semipalatinsk Nuclear Test Sites: Related Issues Thyroid Cancer in Ukraine After the Chernobyl Accident: Incidence, Pathology, Treatment, and Molecular Biol