The thoroughly updated Third Edition of this acclaimed reference covers all aspects of pharmacology and physiology that are relevant to perioperative anesthetic management of patients. Tailored specifically to anesthesiologists' needs, the book provides the current information on drugs and organ functions that is essential for clinical decision-making. The Pharmacology section is organized by drug class and presents key facts on available agents, mechanisms of action, doses, benefits, risks, and drug interactions. The Physiology section, arranged by body system, explains how normal and abnormal body functions impact anesthetic management. This edition includes information on recently introduced and future drugs, new findings on uses and side effects of established agents, and new concepts on organ functions. Complementing the text are more than 600 diagrams--over 100 new to this edition--that clarify chemical structures, drug-induced responses, and physiologic mechanisms. More than 150 tables and a concise drug index are also included.