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BRS Biochemistry, Molecular Biology, and Genetics

by: Swanson, Todd A.; Kim, Sandra I.; Glucksman, Marc J.

BRS Biochemistry, Molecular Biology, and Genetics

by: Swanson, Todd A.; Kim, Sandra I.; Glucksman, Marc J.

ISBN 13:
9780781798754
ISBN 10:
0781798752
Edition: 5th
Format: Paperback
Copyright: 12/07/2009
Publisher: LWW
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Summary

Thoroughly updated for its Fifth Edition, this popular review book is an excellent aid for USMLE Step 1 preparation and for coursework in biochemistry, molecular biology, and genetics. Chapters are written in an outline format and include pedagogical features such as bolded key words, figures, tables, algorithms, and highlighted clinical correlates. USMLE-style questions and answers follow each chapter and a comprehensive exam appears at the end of the book. A companion website includes an interactive question bank with questions from the book and the fully searchable text.

Preface	p. v
Publisher's Preface	p. vii
Acknowledgments	p. ix
Introduction: Organic Chemistry Review	p. 1
Brief Review of Organic Chemistry	p. 1
Acids, Bases, and Buffers	p. 1
Carbohydrate Structure	p. 4
Proteoglycans, Glycoproteins, and Glycolipids	p. 9
Amino Acids	p. 11
Lipids	p. 14
Membranes	p. 16
Nucleotides	p. 18
Review Test	p. 19
Protein Structure and Function	p. 23
General Aspects of Protein Structure	p. 23
Examples of Medically Important Proteins	p. 28
Review Test	p. 34
Enzymes	p. 38
General Properties of Enzymes	p. 38
Dependence of Velocity on Enzyme and Substrate Concentrations, Temperature, and pH	p. 39
The Michaelis-Menten Equation	p. 40
The Lineweaver-Burk Plot	p. 41
Inhibitors	p. 41
Allosteric Enzymes	p. 43
Regulation of Enzyme Activity by Post-Translational (Covalent) Modification	p. 44
Regulation by Protein-Protein Interactions	p. 44
Isoenzymes	p. 45
Review Test	p. 46
Biochemistry of Digestion	p. 50
Digestion of Carbohydrates	p. 50
Digestion of Dietary Triacylglycerol	p. 51
Protein Digestion and Amino Acid Absorption	p. 54
Review Test	p. 57
Glycolysis	p. 63
General Overview	p. 63
Transport of Gulcose into cells	p. 63
Reaction of Glycolysis	p. 64
Special Reactions in Red Blood Cells	p. 66
Regulatory Enzymes of Glycolysis	p. 66
The Fate of Pyruvate	p. 68
Generation of Adenosine Triphosphate by Glycolysis	p. 69
Review Test	p. 72
The Tricarboxylic Acid Cycle, Electron Transport Chain, and Oxidative Metabolism	p. 77
The Tricarboxylic Acid Cycle	p. 77
Electron Transport Chain and Oxidative Phosphorylation	p. 85
Reactive Oxygen Species	p. 90
Review Test	p. 93
Glycogen Metabolism	p. 97
Overview of Glycogen Structure and Metabolism	p. 97
Glycogen Structure	p. 97
Glycogen Synthesis	p. 97
Glycogen Degradation	p. 100
Lysosomal Degradation of Glycogen	p. 101
Regulation of Glycogen Degradation	p. 102
Regulation of Glycogen Synthesis	p. 104
Review Test	p. 105
Gluconeogenesis and the Maintenance of Blood Glucose Levels	p. 109
Overview	p. 109
Reactions of Gluconeogenesis	p. 109
Maintenance of Blood Glucose Levels	p. 114
Review Test	p. 119
Miscellaneous Carbohydrate Metabolism	p. 123
Fructose and Galactose Metabolism	p. 123
Pentose Phosphate Pathway	p. 126
Proteoglycans, Glycoproteins, and Glycolipids	p. 129
Review Test	p. 133
Fatty Acid Metabolism	p. 137
Fatty Acid and Triacylglycerol Synthesis	p. 137
Formation of Triacylglycerol Stores in Adipose Tissue	p. 141
Fatty Acid Oxidation	p. 142
High Yield Comparison from Fatty Acid Synthesis and Oxidation	p. 146
Review Test	p. 147
Cholesterol Metabolism and Blood Lipoproteins	p. 151
Cholesterol and Bile Salt Metabolism	p. 151
Blood Lipoproteins	p. 155
Review Test	p. 159
Ketones and Other Lipid Derivatives	p. 163
Ketone Body Synthesis and Utilization	p. 163
Phospholipid and Sphingolipid Metabolism	p. 165
Metabolism of the Eicosanoids	p. 166
Synthesis of the Steroid Hormones	p. 169
Review Test	p. 172
Amino Acid Metabolism	p. 176
Addition and Removal of Amino Acid Nitrogen	p. 176
Urea Cycle	p. 177
Synthesis and Degradation of Amino Acids	p. 180
Review Test	p. 187
Products Derived From Amino Acids	p. 191
Special Products Derived from Amino Acids	p. 191
Tetrahydrofolate and S-Adenosylmethionine: The One-Carbon Carriers	p. 198
Review Test	p. 201
Nucleotide and Porphyrin Metabolism	p. 203
Purine and Pyrimidine Metabolism	p. 203
Heme Metabolism	p. 208
Review Test	p. 211
Integrative Metabolism and Nutrition	p. 215
Metabolic Fuels and Dietary Requirements	p. 215
Metabolism During the Fed or Absorptive State	p. 219
Fasting	p. 221
Prolonged Fasting (Starvation)	p. 224
Biochemical Functions of Tissues	p. 225
Review Test	p. 229
Molecular Endocrinology	p. 233
General Mechanisms of Hormone Action	p. 233
Regulation of Hormone Levels	p. 236
Actions of Specific Hormones	p. 237
Review Test	p. 247
DNA Replication and Transcription	p. 251
Nucleic Acid Structure	p. 251
Synthesis of DNA (Replication)	p. 256
Synthesis of RNA (Transcription)	p. 262
Review Test	p. 267
RNA Translation and Protein Synthesis	p. 271
Protein Synthesis (Translation of Messenger RNA)	p. 271
Regulation of Protein Synthesis	p. 276
Review Test	p. 282
Genetics	p. 286
Chromosomes	p. 286
Cell Cycle	p. 286
Control of the Cell Cycle	p. 288
Meiosis	p. 289
Gene Dosage	p. 292
Fundamentals of Mendelian Genetics	p. 293
The Punnett Square	p. 294
Modes of Inheritance	p. 294
Moderators of Inheritance	p. 296
Hardy-Weinberg Principle	p. 296
Genetic Testing	p. 297
Review Test	p. 300
Biochemistry of Cancer	p. 305
Oncogenes	p. 305
Tumor-Suppressor Genes	p. 307
Apoptosis	p. 308
Mechanism of Oncogenesis	p. 309
Molecular Carcinogenesis	p. 311
DNA Repair and Carcinogenesis	p. 313
Molecular Progression of Cancer	p. 314
Molecular Markers in Cancer Biology	p. 315
Review Test	p. 316
Techniques in Biochemistry, Molecular Biology, and Genetics	p. 319
Biotechnology Involving Recombinant DNA	p. 319
Technology Involving Proteins	p. 329
Review Test	p. 332
Comprehensive Examination	p. 336
Index	p. 361
Table of Contents provided by Ingram. All Rights Reserved.

Amazon no longer offers textbook rentals. We do!

BRS Biochemistry, Molecular Biology, and Genetics

BRS Biochemistry, Molecular Biology, and Genetics

9780781798754

0781798752

Summary

Table of Contents

Supplemental Materials

Write a Review

Amazon no longer offers textbook rentals. We do!

BRS Biochemistry, Molecular Biology, and Genetics

BRS Biochemistry, Molecular Biology, and Genetics

9780781798754

0781798752

Summary

Table of Contents

Supplemental Materials

Write a Review

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