Designed specifically for the one-semester short course in organic chemistry, this market leader appeals to a range of non-chemistry science majors through its emphasis on practical, real-life applications of chemistry, coverage of basic concepts, and engaging visual style. In contrast to competitors who offer mainly streamlined versions of full-year texts, this text has always been aimed at the short course and its writing style, approach, and selection of topics best suit the needs of this market. The Twelfth Edition further develops the strengths of the previous editions through an updated, dynamic art program--online, on CD, and in the text--new content to keep students current with developments in the organic chemistry field, and a revised lab manual. New! The updated art program offers newly designed electrostatic potential maps and new ball-and-stick structures. The former aid discussions of acid-base chemistry and the latter help students visualize molecules in three dimensions. New! Engaging animations on the Online Study Center further help students visualize chemistry concepts. New! Increased usage of arrow-pushing formalism assists professors teaching reaction mechanisms. New! Problems that emphasize the development of three-dimensional visualization skills have been added. New! A Closer Look At boxes now include coverage of mass spectrometry and carbon dating (Chapter 12), Nobel laureates and protein chemistry (Chapter 17), and the polymerase chain reaction (Chapter 18). These features guide students in using multimedia resources on the web to expand concepts in the text and apply them to real-life examples. Revised! The Laboratory Manual, with the assistance of new co-author T.K. Vinod at Western Illinois University, now includes a new experiment on green chemistry, new pre-laboratory exercises, and revised safety instructions to students. Worked out examples throughout the text along with numerous practice problems guide students through learning and mastering chapter concepts. Within each set of end-of-chapter material, the problems gradually increased in difficulty, reinforcing basic principles and problem-solving skills before moving on to more challenging ones. Engaging A Word About essays motivate students by demonstrating how chemistry relates to other branches of science and to their everyday lives. They include coverage of Quinones and the Bombadier Beetle, Alkaloids and the Dart Poison Frog, Prostaglandins, and Aspirin and Pain.