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Optical coherence tomography is a medical high-resolution imaging technology which offers several distinct advantages over current medical imaging technologies. With a resolution 25x greater than current technologies, its ability to be engineered very small due to its fiber-based design these devices, and it is high speed with frame rates close to video rates, this technology is attracting a great many researchers. This second edition brings together information needed by the various, and sometimes disparate, groups using and studying this technology. It is completely updated throughout with the most recent research and applications. This is not a book on how to build OCT devices, but rather gives a broad treatment of the subject which includes 1) the optics, science, and physics needed to understand the technology; 2) a description of applications with a critical look at how the technology will successfully address actual clinical need; and 3) a discussion of delivery of OCT to the patient, FDA approval and comparisons with available competing technologies. While the required mathematical rigor is present where needed, it is presented in such a way that non-scientists and non-engineers will still be able to gain a basic understanding of OCT and the applications, as well as the issues of bringing the technology to the market. Revised throughout, comprehensive guide to Optical Coherence Tomography, including the most recent research in context and thoroughly explained Provides non-scientists and non-engineers basic understanding of Optical Coherence Tomography applications and issues. Written by one of the pioneers of Optical Coherence Tomography.