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Janeway's Immunobiology, Seventh Edition is an introductory text for use in immunology courses for undergraduates, graduate students and medical students. It guides the reader through the immune system in all its aspects - from the first engagement of innate immunity to the generation of the adaptive immune response and its clinical consequences. The Seventh Edition has been comprehensively updated throughout, and includes new information on topics such as NK cells, Toll-like receptors, AID, viral evasins, mucosal immunity, and celiac disease, to name a few. Each copy of the book includes a revised CD-ROM, Immunobiology Interactive, which contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes. Janeway's Immunobiologycontinues to set the standard for currency and authority with its clear writing style and organization, full-color art program, scientific accuracy and consistent viewpoint - that of the host's interaction with an environment containing many species of potentially harmful microorganisms.
Kenneth Murphy is a Professor and Co-Director of Immunobiology and Investigation of the Howard Hughes Medical Institute in the Department of Pathology and Immunology at Washington University School of Medicine, St. Louis.
Table of Contents
An Introduction to Immunobiology and Innate Immunity
Basic Concepts in Immunology
The Recognition of Antigen
Antigen Recognition by B-cell and T-cell Receptors
The Generation of Lymphocyte Antigen Receptors
Antigen Presentation to T Lymphocytes
The Development of Mature Lymphocyte Receptor Repertoires
Signalling Through Immune System Receptors
The Development and Survival of Lymphocytes
The Adaptive Immune Response
T Cell-Mediated Immunity
The Humoral Immune Response
Dynamics of Adaptive Immunity
The Mucosal Immune System
The Immune System in Health and Disease
Failures of Host Defense Mechanism
Allergy and Hypersensitivity
Autoimmunity and Transplantation
Manipulation of the Immune Response
The Origins of Immune Responses
Evolution of the Immune System
Cytokines and their Receptors
Chemokines and their Receptors
Table of Contents provided by Blackwell. All Rights Reserved.