The most widely read textbook in the history of medicine made more essential to practice and education by an unmatched array of multi-media contentThrough six decades, no resource has matched the encyclopedic scope, esteemed scholarship, and scientific rigor ofHarrison's Principles of Internal Medicine, both as a textbook and as a clinical reference. It remains the most universally respected textbook in all of medical publishing and the pinnacle of current medical knowledge.The eighteenth edition ofHarrison'sfeatures expanded and more in-depth coverage of key issues in clinical medicine, pathophysiology, and medical education. The acclaimedHarrison'sDVD has been updated to include 53 chapters not found in the text; 14 all-new how-to videos commissioned specifically forHarrison's; PowerPoint presentations on essential topics in medical education; and hundreds of bonus illustrations. Presented in two volumes NEW text design greatly enhances readability NEW chapters on cutting-edge topics in clinical medicine Expanded focus on global considerations of health and diseaseEditor-in-Chief: Dan Longo, MD (Boston, MA)is Professor of Medicine, Brigham and Women's Hospital/Harvard Medical School.