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Goodman & Gilman's The Pharmacological Basis of Therapeutics, Eleventh Edition

by: Brunton, Laurence L., Ph.D.; Lazo, John S.; Parker, Keith L., M.D., Ph.D.; Goodman, Louis Sanford

Goodman & Gilman's The Pharmacological Basis of Therapeutics, Eleventh Edition

by: Brunton, Laurence L., Ph.D.; Lazo, John S.; Parker, Keith L., M.D., Ph.D.; Goodman, Louis Sanford

ISBN 13:
9780071422802
ISBN 10:
0071422803
Edition: 11th
Format: Hardcover
Copyright: 08/23/2005
Publisher: McGraw-Hill Professional
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Summary

The undisputed leader in medical pharmacology, without equal. Updated to reflect all critical new developments in drug action and drug-disease interaction. This is the "desert island" book of all medical pharmacologyif you can own just one pharmacology book, this is it.

Contributors

Consultants to the Editors

xvii

Preface

xxi

Preface to the First Edition

xxiii

SECTION I GENERAL PRINCIPLES

(136)

Pharmacokinetics and Pharmacodynamics: The Dynamics of Drug Absorption, Distribution, Action, and Elimination

(40)

Iain L. O. Buxton

Membrane Transporters and Drug Response

(30)

Kathleen M. Ciacomini

Yuichi Sugiyama

Drug Metabolism

(22)

Frank J. Gonzalez

Robert H. Tukey

Pharmacogenetics

(24)

Mary V. Relling

Kathleen M. Giacomini

The Science of Drug Therapy

117

(20)

John A. Oates

SECTION II DRUGS ACTING AT SYNAPTIC AND NEUROEFFECTOR JUNCTIONAL SITES

137

(180)

Neurotransmission: The Autonomic and Somatic Motor Nervous Systems

137

(46)

Thomas C. Westfall

David P. Westfall

Muscarinic Receptor Agonists and Antagonists

183

(18)

Joan Heller Brown

Palmer Taylor

Anticholinesterase Agents

201

(16)

Palmer Taylor

Agents Acting at the Neuromuscular Junction and Autonomic Ganglia

217

(20)

Palmer Taylor

Adrenergic Agonists and Antagonists

237

(60)

Thomas C. Westfall

David P. Westfall

5-Hydroxytryptamine (Serotonin): Receptor Agonists and Antagonists

297

(20)

Elaine Sanders-Bush

Steven E. Mayer

SECTION III DRUGS ACTING ON THE CENTRAL NERVOUS SYSTEM

317

(312)

Neurotransmission and the Central Nervous System

317

(24)

Floyd E. Bloom

General Anesthetics

341

(28)

Alex S. Evers

C. Michael Crowder

Jeffrey R. Balser

Local Anesthetics

369

(18)

William A. Catterall

Ken Mackie

Therapeutic Gases: Oxygen, Carbon Dioxide, Nitric Oxide, and Helium

387

(14)

Brett A. Simon

Eric J. Moody

Roger A. Johns

Hypnotics and Sedatives

401

(28)

Dennis S. Charney

S. John Mihic

R. Adron Harris

Drug Therapy of Depression and Anxiety Disorders

429

(32)

Ross J. Baldessarini

Pharmacotherapy of Psychosis and Mania

461

(40)

Ross J. Baldessarini

Frank I. Tarazi

Pharmacotherapy of the Epilepsies

501

(26)

James O. McNamara

Treatment of Central Nervous System Degenerative Disorders

527

(20)

David G. Standaert

Anne B. Young

Opioid Analgesics

547

(44)

Howard B. Gutstein

Huda Akil

Ethanol

591

(16)

Michael F. Fleming

S. John Mihic

R. Adron Harris

Drug Addiction and Drug Abuse

607

(22)

Charles P. O'Brien

SECTION IV AUTACOIDS: DRUG THERAPY OF INFLAMMATION

629

(108)

Histamine, Bradykinin, and Their Antagonists

629

(24)

Randal A. Skidgel

Ervin G. Erdos

Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor

653

(18)

Emer M. Smyth

Anne Burke

Garret A. FitzGerald

Analgesic-Antipyretic Agents; Pharmacotherapy of Gout

671

(46)

Anne Burke

Emer M. Smyth

Garret A. FitzGerald

Pharmacotherapy of Asthma

717

(20)

Bradley J. Undem

SECTION V DRUGS AFFECTING RENAL AND CARDIOVASCULAR FUNCTION

737

(230)

Diuretics

737

(34)

Edwin K. Jackson

Vasopressin and Other Agents Affecting the Renal Conservation of Water

771

(18)

Edwin K. Jackson

Renin and Angiotensin

789

(34)

Edwin K. Jackson

Treatment of Myocardial Ischemia

823

(22)

Thomas Michel

Therapy of Hypertension

845

(24)

Brian B. Hoffman

Pharmacotherapy of Congestive Heart Failure

869

(30)

Thomas P. Rocco

James C. Fang

Antiarrhythmic Drugs

899

(34)

Dan M. Roden

Drug Therapy for Hypercholesterolemia and Dyslipidemia

933

(34)

Robert W. Mahley

Thomas P. Bersot

SECTION VI DRUGS AFFECTING GASTROINTESTINAL FUNCTION

967

(54)

Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease

967

(16)

Willemijntje A. Hoogerwerf

Pankaj Jay Pasricha

Treatment of Disorders of Bowel Motility and Water Flux; Antiemetics; Agents Used in Biliary and Pancreatic Disease

983

(26)

Pankaj Jay Pasricha

Pharmacotherapy of Inflammatory Bowel Disease

1009

(12)

Joseph H. Sellin

Pankaj Jay Pasricha

SECTION VII CHEMOTHERAPY OF PARASITIC INFECTIONS

1021

(74)

Chemotherapy of Protozoal Infections: Malaria

1021

(28)

Theresa A. Shapiro

Daniel E. Goldberg

Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections

1049

(24)

Margaret A. Phillips

Samuel L. Stanley, Jr.

Chemotherapy of Helminth Infections

1073

(22)

Alex Loukas

Peter J. Hotez

SECTION VIII CHEMOTHERAPY OF MICROBIAL DISEASES

1095

(220)

General Considerations of Antimicrobial Therapy

1095

(16)

Henry F. Chambers

Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections

1111

(16)

William A. Petri, Jr.

Penicillins, Cephalosporins, and Other β-Lactam Antibiotics

1127

(28)

William A. Petri, Jr.

Aminoglycosides

1155

(18)

Henry F. Chambers

Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents

1173

(30)

Henry F. Chambers

Chemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, and Leprosy

1203

(22)

William A. Petri, Jr.

Antifungal Agents

1225

(18)

John E. Bennett

Antiviral Agents (Nonretroviral)

1243

(30)

Frederick G. Hayden

Antiretroviral Agents and Treatment of HIV Infection

1273

(42)

Charles Flexner

SECTION IX CHEMOTHERAPY OF NEOPLASTIC DISEASES

1315

(90)

Antineoplastic Agents

1315

(90)

Bruce A. Chabner

Philip C. Amrein

Brian Druker

M. Dror Michaelson

Constantine S. Mitsiades

Paul E. Goss

David P. Ryan

Sumant Ramachandra

Paul G. Richardson

Jeffrey G. Supko

Wyndham H. Wilson

SECTION X IMMUNOMODULATORS

1405

(28)

Immunosuppressants, Tolerogens, and Immunostimulants

1405

(28)

Alan M. Krensky

Flavio Vincenti

William M. Bennett

SECTION XI DRUGS ACTING ON THE BLOOD AND THE BLOOD-FORMING ORGANS

1433

(56)

Hematopoietic Agents: Growth Factors, Minerals, and Vitamins

1433

(34)

Kenneth Kaushansky

Thomas J. Kipps

Blood Coagulation and Anticoagulant, Thrombolytic, and Antiplatelet Drugs

1467

(22)

Philip W. Majerus

Douglas M. Tollefsen

SECTION XII HORMONES AND HORMONE ANTAGONISTS

1489

(190)

Pituitary Hormones and Their Hypothalamic Releasing Factors

1489

(22)

Keith L. Parker

Bernard P. Schimmer

Thyroid and Antithyroid Drugs

1511

(30)

Alan P. Farwell

Lewis E. Braverman

Estrogens and Progestins

1541

(32)

David S. Loose

George M. Stancel

Androgens

1573

(14)

Peter J. Snyder

Adrenocorticotropic Hormone; Adrenocortical Steroids and Their Synthetic Analogs; Inhibitors of the Synthesis and Actions of Adrenocortical Hormones

1587

(26)

Bernard P. Schimmer

Keith L. Parker

Insulin, Oral Hypoglycemic Agents, and the Pharmacology of the Endocrine Pancreas

1613

(34)

Stephen N. Davis

Agents Affecting Mineral Ion Homeostasis and Bone Turnover

1647

(32)

Peter A. Friedman

SECTION XIII DERMATOLOGY

1679

(60)

Dermatological Pharmacology

1679

(28)

Lindy P. Fox

Hans F. Merk

David R. Bickers

SECTION XIV OPHTHALMOLOGY

Ocular Pharmacology

1707

(32)

Jeffrey D. Henderer

Christopher J. Rapuano

SECTION XV TOXICOLOGY

1739

(150)

Principles of Toxicology and Treatment of Poisoning

1753

(1)

Curtis D. Klaassen

Heavy Metals and Heavy-Metal Antagonists

1753

(136)

Curtis D. Klaassen

APPENDICES

I. Principles of Prescription Order Writing and Patient Compliance

1777

(10)

Iain L.O. Buxton

II. Design and Optimization of Dosage Regimens; Pharmacokinetic Data

1787

(102)

Kenneth E. Thummel

Danny D. Shen

Nina Isoherranen

Helen E. Smith

Index

1889

Amazon no longer offers textbook rentals. We do!

Goodman & Gilman's The Pharmacological Basis of Therapeutics, Eleventh Edition

Goodman & Gilman's The Pharmacological Basis of Therapeutics, Eleventh Edition

9780071422802

0071422803

Summary

Table of Contents

Supplemental Materials

Write a Review

Amazon no longer offers textbook rentals. We do!

Goodman & Gilman's The Pharmacological Basis of Therapeutics, Eleventh Edition

Goodman & Gilman's The Pharmacological Basis of Therapeutics, Eleventh Edition

9780071422802

0071422803

Summary

Table of Contents

Supplemental Materials

Write a Review

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