Over the past 10 years, combinatorial and high-throughput experimental approaches and related informatics, modeling and data-mining methods have permitted researchers to accelerated the pace at which new, complex materials and devices systems are discovered, optimized and understood. Today, the development and application of these revolutionary approaches continue to grow and diversify, as evidenced by a plethora of advances and successful studies emerging from a wide variety of universities, national laboratories and industry research groups across the globe.