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Wintrobe's Clinical Hematology

by: Lee, G. Richard; Foerster, John, M.D.; Lukens, John N., M.D.; Paraskevas, Frixos, M.D.

Wintrobe's Clinical Hematology

by: Lee, G. Richard; Foerster, John, M.D.; Lukens, John N., M.D.; Paraskevas, Frixos, M.D.

ISBN 13:
9780683182422
ISBN 10:
0683182420
Format: Hardcover
Copyright: 09/01/1998
Publisher: Williams & Wilkins

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Summary

Univ. of Utah, Salt Lake City. Two-volume reference includes the progress of the field of hematology over the past 55 years. Previous edition: c1993. New chapters on immuno- therapy, gene therapy and myelodysplastic syndromes have been added. Halftone and color illustrations. DNLM: Blood.

Preface

vii

(2)

Contributors

PART I. INTRODUCTION

(6)

1. The Diagnostic and Therapeutic Approach to Hematologic Problems

Maxwell M. Wintrobe

PART II. LABORATORY HEMATOLOGY

(136)

2. Examination of the Blood and Bone Marrow

(27)

Sherrie L. Perkins

3. Immunodiagnosis

(20)

Frixos Paraskevas

John Foerster

4. Clinical Flow Cytometry

(16)

Frixos Paraskevas

5. Clusters of Differentiation

(26)

Frixos Paraskevas

6. Cytogenetics

(26)

Maria R. Baer

7. Molecular Genetics and Hematology

124

(21)

Rebecca L.Shattuck-Brandt

Stephen J. Brandt

PART III. THE NORMAL HEMATOLOGIC SYSTEM

145

(752)

Section 1. Hematopoiesis

8. Origin and Development of Blood Cells

145

(24)

Maurice C. Bondurant

Mark J. Koury

Section 2. The Erythrocyte

9. Erythropoiesis

169

(24)

Emmanuel N. Dessypris

10. The Mature Erythrocyte

193

(35)

Marilyn J. Telen

Russel E. Kaufman

11. Nutritional Factors in the Production and Function of Erythrocytes

228

(39)

G. Richard Lee

Victor D. Herbert

12. Destruction of Erythrocytes

267

(33)

Andrew Deiss

Section 3. Granulocytes and Monocytes

13. Neutrophilic Leukocytes

300

(51)

Keith M. Skubitz

14. The Human Eosinophil

351

(11)

Redwan Moqbel

Allan B. Becker

15. Basophilic Leukocytes: Mast Cells and Basophils

362

(15)

A. Dean Befus

Judah A. Denburg

16. Mononuclear Phagocytes

377

(38)

J. Brice Weinberg

17. Phagocytosis

415

(15)

Frixos Paraskevas

Section 4. The Lymphocytes

18. The Lymphatic System

430

(34)

Frixos Paraskevas

John Foerster

19. B Lymphocytes

464

(33)

Frixos Paraskevas

20. T Lymphocytes and NK Cells

497

(47)

Frixos Paraskevas

21. Cell Interactions in the Immune Response

544

(71)

Frixos Paraskevas

Section 5. Hemostasis

22. Platelets and Megakaryocytes

615

(46)

Paula E. Stenberg

Ronald J. Hill

23. Platelets in Hemostasis and Thrombosis

661

(23)

Leslie V. Parise

Christel Boudignon-Proudhon

Patricia J. Keely

Ulhas P. Naik

24. Blood Coagulation and Fibrinolysis

684

(81)

Charles S. Greenberg

Carolyn L. Orthner

25. Endothelium and the Regulation of Hemostasis

765

(9)

George M. Rodgers

Section 6. Transfusion and Transplantation

26. Red Cell, Platelet, and White Cell Antigens

774

(43)

Marlis L. Schroeder

27. Principles and Practice of Transfusion Medicine

817

(58)

Marlis L. Schroeder

28. Hematopoietic Stem Cell Transplantation

875

(22)

Richard A. Nash

PART IV. DISORDERS OF RED CELLS

897

(660)

Section 1. Anemia: General Considerations

29. Anemia: General Aspects

897

(11)

G. Richard Lee

30. Anemia: a Diagnostic Strategy

908

(33)

G. Richard Lee

Section 2. Megaloblastic Anemias: Disorders of Impaired DNA Synthesis

31. Pernicious Anemia and Other Causes of Vitamin B12 (Cobalamin) Deficiency

941

(24)

G. Richard Lee

32. Folate Deficiency: Causes and Management

965

(8)

G. Richard Lee

33. Inherited and Drug-Induced Megaloblastic Anemia

973

(6)

G. Richard Lee

Section 3. Disorders of Iron Metabolism and Heme Synthesis

34. Iron Deficiency and Iron-Deficiency Anemia

979

(32)

G. Richard Lee

35. The Anemia of Chronic Disorders

1011

(11)

Robert T. Means, Jr

36. Sideroblastic Anemias

1022

(24)

Sylvia S. Bottomley

37. Methemoglobinemia and Other Disorders Accompanied by Cyanosis

1046

(10)

John N. Lukens

38. Hemochromatosis

1056

(15)

Corwin Q. Edwards

39. Porphyria

1071

(38)

Sylvia S. Bottomley

G. Richard Lee

Section 4. Hemolytic Anemia

40. Hemolytic Disorders: General Considerations

1109

(23)

G. Richard Lee

41. Hereditary Spherocytosis and Other Anemias Due to Abnormalities of the Red Cell Membrane

1132

(28)

Bertil E. Glader

John N. Lukens

42. Hereditary Hemolytic Anemias Associated with Abnormalities of Erythrocyte Glycolysis and Nucleotide Metabolism

1160

(16)

Bertil E. Glader

John N. Lukens

43. Glucose-6-Phosphate Dehydrogenase Deficiency and Related Disorders of Hexose Monophosphate Shunt and Glutathione Metabolism

1176

(15)

Bertil E. Glader

John N. Lukens

44. Mechanisms of Immune Destruction of Erythrocytes

1191

(19)

Charles J. Parker

John Foerster

45. Alloimmune Hemolytic Disease of the Fetus and Newborn

1210

(23)

John M. Bowman

46. Autoimmune Hemolytic Anemias

1233

(31)

Anne T. Thomas

47. Paroxysmal Nocturnal Hemoglobinuria

1264

(25)

Charles J. Parker

G. Richard Lee

48. Acquired Hemolytic Anemias Resulting from Direct Effects of Infectious, Chemical, or Physical Agents

1289

(16)

G. Richard Lee

49. Red Cell Fragmentation Syndromes

1305

(24)

John Foerster

Section 5. Hereditary Disorders of Hemoglobin Structure and Synthesis

50. The Abnormal Hemoglobins: General Principles

1329

(17)

John N. Lukens

51. Sickle Cell Anemia and Other Sickling Syndromes

1346

(52)

Winfred C. Wang

John N. Lukens

52. Unstable Hemoglobin Disease

1398

(7)

John N. Lukens

G. Richard Lee

53. The Thalassemias and Related Disorders: Quantitative Disorders of Hemoglobin Synthesis

1405

(44)

John N. Lukens

Section 6. Other Disorders Associated with Anemia

54. Pancytopenia, Aplastic Anemia, and Pure Red Cell Aplasia

1449

(36)

Darryl M. Williams

55. Acute Post-Hemorrhagic Anemia

1485

(4)

G. Richard Lee

56. Congenital Dyserythropoietic Anemias

1489

(8)

G.Richard Lee

57. The Anemias Associated with Renal Disease, Liver Disease, Endocrine Disease, and Pregnancy

1497

(21)

G. Richard Lee

58. Anemias Unique to Infants and Young Children

1518

(20)

Jeffrey D. Hord

John N. Lukens

Section 7. Erythrocytosis

59. Polycythemia: Erythrocytosis

1538

(19)

Robert T. Means, Jr

PART V. DISORDERS OF HEMOSTASIS AND COAGULATION

1557

(264)

Section 1. Introduction

60. The Diagnostic Approach to the Bleeding Disorders

1557

(22)

George M. Rodgers

Thomas C. Bithell

Section 2. Thrombocytopenia

61. Thrombocytopenia: Pathophysiology and Classification

1579

(4)

Shirley Parker Levine

62. Thrombocytopenia Caused by Immunologic Platelet Destruction

1583

(29)

Shirley Parker Levine

63. Thrombotic Thrombocytopenic Purpura and Other Forms of Nonimmunologic Platelet Destruction

1612

(11)

Shirley Parker Levine

64. Miscellaneous Causes of Thrombocytopenia

1623

(10)

Shirley Parker Levine

Section 3. Other Disorders of Primary Hemostasis

65. Bleeding Disorders Caused by Vascular Abnormalities

1633

(15)

Mathew M. Rees

George M. Rodgers

66. Thrombocytosis

1648

(13)

Shirley Parker Levine

67. Qualitative Disorders of Platelet Function

1661

(21)

Shirley Parker Levine

Section 4. Coagulation Disorders

68. Inherited Coagulation Disorders

1682

(51)

George M. Rodgers

Charles S. Greenberg

69. Acquired Coagulation Disorders

1733

(48)

Alan B.M. Grosset

George M. Rodgers

Section 5. Thrombosis

70. Thrombosis and Antithrombotic Therapy

1781

(40)

George M. Rodgers

PART VI. NONMALIGNANT DISORDERS OF LEUKOCYTES, THE SPLEEN, AND/OR IMMUNOGLOBINS

1821

(172)

71. Diagnostic Approach to Malignant and Nonmalignant Disorders of the Hematopoietic-Lymphoid System

1821

(15)

Thomas L. McCurley

John P. Greer

72. Variations of Leukocytes in Disease

1836

(26)

James C. Gay

John W. Athens

73. Neutropenia

1862

(27)

Raymond G. Watts

74. Qualitative Disorders of Leukocytes

1889

(19)

Keith M. Skubitz

75. Abnormalities of the Monocyte-Macrophage System--The Lysosomal Storage Diseases

1908

(8)

Margaret M. McGovern

Robert J. Desnick

76. Langerhans Cell Histiocytosis

1916

(10)

H. Stacy Nicholson

John N. Lukens

77. Infectious Mononucleosis

1926

(30)

John Foerster

78. Hematologic Aspects of Acquired Immunodeficiency Disease

1956

(13)

Robert L. Janco

79. Disorders of the Spleen

1969

(24)

William C. Chapman

Martin Newman

PART VII. HEMATOLOGIC MALIGNANCIES

1993

(745)

Section 1. General Aspects

80. The Hematopoietic-Lymphoid Neoplasms

1993

(40)

John B. Cousar

Charles L. Sawyers

Stephan W. Morris

Martin U. Kuefer

81. Complications of Hematopoietic Neoplasms

2033

(43)

Edward R. Arrowsmith

John P. Greer

William R. Macon

82. Principles and Pharmacology of Chemotherapy

2076

(26)

Kenneth R. Hande

83. Supportive Care in Hematologic Malignancies

2102

(55)

Asha Kallianpur

84. Immunotherapy

2157

(21)

Stanford J. Stewart

85. Gene Therapy for Hematologic Disorders, HIV Infection, and Cancer

2178

(31)

John F. Tisdale

Cynthia E. Dunbar

Stacey A. Goodman

Section 2. The Acute Leukemias

86. Classification and Differentiation of the Acute Leukemias

2209

(32)

Marsha C. Kinney

John N. Lukens

87. Acute Lymphocytic Leukemia

2241

(31)

James A. Whitlock

Paul S. Gaynon

88. Acute Myelogenous Leukemia

2272

(48)

John P. Greer

Maria R. Baer

Marsha C. Kinney

89. The Myelodysplastic Syndromes

2320

(22)

Alan F. List

Donald C. Doll

Section 3. Myeloproliferative Disorders

90. Chronic Myeloid Leukemia

2342

(32)

Richard S. Larson

Steven N. Wolff

91. Polycythemia Vera

2374

(16)

Robert T. Means, Jr

92. Myelofibrosis

2390

(15)

Douglas A. Clark

Wilbur L. Williams

Section 4. Lymphoproliferative Disorders

93. Chronic Lymphocytic Leukemia

2405

(23)

James B. Johnston

94. Hairy Cell Leukemia

2428

(19)

James B. Johnston

95. Non-Hodgkin Lymphomas

2447

(91)

John P. Greer

William R. Macon

Thomas L. McCurley

96. Hodgkin Disease

2538

(34)

Richard S. Stein

97. Cutaneous T-Cell Lymphoma: Mycosis Fungoides and Sezary Syndrome

2572

(40)

John A. Zic

Kevin E.Salhany

John P. Greer

Lloyd E. King, Jr

Section 5. Plasma Cell Dyscrasias

98. Plasma Cell Dyscrasias: General Considerations

2612

(19)

John Foerster

99. Multiple Myeloma

2631

(50)

John Foerster

Frixos Paraskevas

Waldenstrom Macroglobulinemia

2681

(12)

John Foerster

101. Heavy Chain Diseases

2681

(12)

John Foerster

102. Amyloidosis

2705

(20)

John Foerster

103. Cryoglobulins and Cryoglobulinemia

2725

(13)

John Foerster

APPENDICES

2738

Appendix A. Normal Blood and Bone Marrow Values in Humans

2738

(11)

Sherrie L. Perkins

Appendix B. Comparative Hematology

2749

Harvey A. Ragan

INDEX

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Wintrobe's Clinical Hematology

Wintrobe's Clinical Hematology

9780683182422

0683182420

Summary

Table of Contents

Supplemental Materials

Write a Review

Amazon no longer offers textbook rentals. We do!

Wintrobe's Clinical Hematology

Wintrobe's Clinical Hematology

9780683182422

0683182420

Summary

Table of Contents

Supplemental Materials

Write a Review

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