Since the publication of the first edition, the field of microarrays has evolved. This timely second edition replaces the commercial software with the open source R computing environment. Although R code is integrated into the text, users of other programming languages can still benefit from the book. This edition contains new chapters on cutting-edge microarray topics and provides the R code on an accompanying CD-ROM. Richly illustrated in full color, the book continues to bridge the gap between an introduction to data analysis and advanced material for performing data analysis.