Completely updated and expanded for its Second Edition, this comprehensive guide combines the best elements of a diseases reference and a full-color atlas in one clinical reference for every practice setting. The book focuses on the pathophysiologic processes behind more than 450 disorders, ensuring that practitioners fully understand the pathophysiologic rationale behind focused assessments, signs and symptoms, diagnostic tests, and treatments. This edition includes the newest diseases, diagnostic tests, and treatments. New icons highlight genetic discoveries and indicate multisystem disorders requiring a focused multidisciplinary approach. This edition also includes patient teaching handouts that can be copied and given to patients.