The Oxford Textbook of Rheumatology is an exciting and innovative new work which emphasizes the basic sciences and serves as a practical guide for the clinician. The international roster of expert contributors underlines the wide interest in this field, and each contributor was selected on the basis of expertise and high profile in each sub-specialty. Whenever possible, the authors have approached the subject in a problem-oriented way. The book demonstrates how molecular biology helps us to understand the etiology of rheumatic disease, as well as presenting a wide range of clinical problems which commonly face the practicing rheumatologist. The interactive nature of modern medicine is emphasized by presenting a series of chapters co-authored by specialists in other fields such as cardiology and neurology. The scientific basis of rheumatic disease is described in terms of molecular genetics, immunology, and developmental biology, and future directions for research are identified. The investigation and diagnosis of rheumatic disease are described in a series of chapters incorporating techniques from the simplest hematological tests to MRI scanning techniques. High-quality clinical pictures illustrate this important work and imaging techniques are described in detail. Of particular interest is the presentation of the similarities and differences in rheumatic disease according to age group, as described in relevant chapters written by pediatricians and geriatricians. Finally, all aspects of surgical management and rehabilitation are carefully considered, and newer forms of therapy are highlighted in discussion.