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Mechanisms of Exocytosis

ISBN: 9781573317351 | 1573317357
Edition: 1st
Format: Paperback
Publisher: Wiley-Blackwell
Pub. Date: 2/9/2009

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SummaryTable of Contents
The volume provides an overview of the current status of exocytosis and to define future goals.Exocytosis, a universal process of eukaryotic cells, consisting of the fusion between the vesicle and the plasma membrane is an important topic in cell biology, physiology, biophysics, biochemistry and many other disciplines. The understanding of this rather complex process is essential for the understanding of normal function of unicellular and multicellular organisms from animal to plant kingdoms and in pathological conditions as well. During the la... MORE
Overview: Exocytosis Continues to Amaze Usp. ix
Vesicle Dynamics and Cell Types
Rhythmic Kinetics of Single Fusion and Fission in a Plant Cell Protoplastp. 1
Fluorescent Cargo Proteins in Peptidergic Endocrine Cells: Cell Type Determines Secretion Kinetics at Exocytosisp. 7
Apical Plasma Membrane Traffic in Superficial Cells of Bladder Urotheliump. 18
Regulated Exocytosis and Vesicle Trafficking in Ast... MOREp. 30
Ca2+-Dependent Actin Coating of Lamellar Bodies after Exocytotic Fusion: A Prerequisite for Content Release or Kiss-and-Runp. 43
Exocytosis of Insulin: In Vivo Maturation of Mouse Endocrine Pancreasp. 53
Compound Exocytosis in Pituitary Cellsp. 63
Molecular Mechanisms of Exocytosis
The Functions of Munc 18-1 in Regulated Exocytosisp. 76
Voltage-gated Potassium Channel as a Facilitator of Exocytosisp. 87
SNAP-25 in Neuropsychiatric Disordersp. 93
Exocytosis, Mediatophore, and Vesicular Ca2+/H+ Antiport in Rapid Neurotransmissionp. 100
Single Molecule Probing of SNARE Proteins by Atomic Force Microscopyp. 113
Identifying Critical Components of Native Ca2+-triggered Membrane Fusion: Integrating Studies of Proteins and Lipidsp. 121
The Fusion Pore and Vesicle Cargo Discharge Modulationp. 135
SNAP-25 and Gene-targeted Mouse Mutantsp. 145
Rescuing the Subprime Meltdown in Insulin Exocytosis in Diabetesp. 154
Intracellular Messengers and Exocytosis
Phosphatidylinositol-4,5-bisphosphate-dependent Facilitation of the ATP-dependent Secretory Activity in Mouse Pituitary Cellsp. 165
Multiple Roles of Gi/o Protein-coupled Receptors in Control of Action Potential Secretion Coupling in Pituitary Lactotrophsp. 174
Exocytotic Properties of Human Pancreatic ß-cellsp. 187
Expression of Dense-core Vesicles and of Their Exocytosis Are Governed by the Repressive Transcription Factor NRSF/RESTp. 194
The Coffin-Lowry Syndrome-associated Protein RSK2 Controls Neuroendocrine Secretion through the Regulation of Phospholipase D1 at the Exocytotic Sitesp. 201
Calcium-regulated Exocytosis in Neuroendocrine Cells: Intersectin-1L Stimulates Actin Polymerization and Exocytosis by Activating Cdc42p. 209
A Neurotoxic Secretory Phospholipase A2 Induces Apoptosis in Motoneuron-like Cellsp. 215
Index of Contributorsp. 225
Table of Contents provided by Ingram. All Rights Reserved.


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