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| Preface | p. viii |
| Introduction / Embryology: Clinical Relevance and Historical Perspective | p. xii |
| General Embryology | p. 1 |
| Introduction to Molecular Regulation and Signaling | p. 3 |
| Gene Transcription | p. 3 |
| Other Regulators of Gene Expression | p. 5 |
| Induction and Organ Formation | p. 5 |
| Cell Signaling | p. 6 |
| Gametogenesis: Conversion of Germ Cells... MORE | p. 10 |
| Primordial Germ Cells | p. 10 |
| The Chromosome Theory of Inheritance | p. 11 |
| Morphological Changes During Maturation of the Gametes | p. 21 |
| First Week of Development: Ovulation to Implantation | p. 29 |
| Ovarian Cycle | p. 29 |
| Fertilization | p. 32 |
| Cleavage | p. 37 |
| Blastocyst Formation | p. 37 |
| Uterus at Time of Implantation | p. 39 |
| Second Week of Development: Bilaminar Germ Disc | p. 43 |
| Day 8 | p. 43 |
| Day 9 | p. 43 |
| Days 11 and 12 | p. 44 |
| Day 13 | p. 46 |
| Third Week of Development: Trilaminar Germ Disc | p. 51 |
| Gastrulation: Formation of Embryonic Mesoderm and Endoderm | p. 51 |
| Formation of the Notochord | p. 51 |
| Establishment of the Body Axes | p. 52 |
| Fate Map Established During Gastrulation | p. 57 |
| Growth of the Embryonic Disc | p. 57 |
| Further Development of the Trophoblast | p. 59 |
| Third to Eighth Weeks: The Embryonic Period | p. 63 |
| Derivatives of the Ectodermal Germ Layer | p. 63 |
| Derivatives of the Mesodermal Germ Layer | p. 70 |
| Derivatives of the Endodermal Germ Layer | p. 78 |
| Patterning of the Anteroposterior Axis: Regulation by Homeobox Genes | p. 81 |
| External Appearance During the Second Month | p. 81 |
| The Gut Tube and the Body Cavities | p. 86 |
| A Tube on Top of a Tube | p. 86 |
| Formation of the Body Cavity | p. 87 |
| Serous Membranes | p. 88 |
| Diaphragm and Thoracic Cavity | p. 90 |
| Formation of the Diaphragm | p. 92 |
| Third Month to Birth: The Fetus and Placenta | p. 96 |
| Development of the Fetus | p. 96 |
| Fetal Membranes and Placenta | p. 100 |
| Chorion Frondosum and Decidua Basalis | p. 102 |
| Structure of the Placenta | p. 103 |
| Amnion and Umbilical Cord | p. 107 |
| Placental Changes at the End of Pregnancy | p. 108 |
| Amniotic Fluid | p. 109 |
| Fetal Membranes in Twins | p. 110 |
| Parturition (Birth) | p. 115 |
| Birth Defects and Prenatal Diagnosis | p. 117 |
| Birth Defects | p. 117 |
| Prenatal Diagnosis | p. 125 |
| Fetal Therapy | p. 128 |
| Systems-Based Embryology | p. 131 |
| The Axial Skeleton | p. 133 |
| Skull | p. 133 |
| Vertebrae and the Vertebral Column | p. 142 |
| Ribs and Sternum | p. 144 |
| Muscular System | p. 145 |
| Striated Skeletal Musculature | p. 145 |
| Innervation of Axial Skeletal Muscles | p. 146 |
| Skeletal Muscle and Tendons | p. 148 |
| Mclecular Regulation of Muscle Development | p. 148 |
| Patterning of Muscles | p. 148 |
| Head Musculature | p. 148 |
| Limb Musculature | p. 148 |
| Cardiac Muscle | p. 149 |
| Smooth Muscle | p. 149 |
| Limbs | p. 151 |
| Limb Growth And Development | p. 151 |
| Limb Musculature | p. 152 |
| Cardiovascular System | p. 162 |
| Establishment and Patterning of the Primary Heart Field | p. 162 |
| Formation and Position of the Heart Tube | p. 164 |
| Formation of the Cardiac Loop | p. 166 |
| Molecular Regulation of Cardiac Development | p. 169 |
| Development of the Sinus Venosus | p. 170 |
| Formation of the Cardiac Septa | p. 171 |
| Formation of the Conducting System of the Heart | p. 185 |
| Vascular Development | p. 185 |
| Circulation Before and After Birth | p. 195 |
| Respiratory System | p. 201 |
| Formation of the Lung Buds | p. 201 |
| Larynx | p. 203 |
| Trachea, Bronchi, And Lungs | p. 203 |
| Maturation of the Lungs | p. 205 |
| Digestive System | p. 208 |
| Divisions of the Gut Tube | p. 208 |
| Molecular Regulation of Gut Tube Development | p. 209 |
| Mesenteries | p. 210 |
| Foregut | p. 211 |
| Molecular Regulation of Liver Induction | p. 219 |
| Pancreas | p. 221 |
| Midgut | p. 222 |
| Hindgut | p. 229 |
| Urogenital System | p. 232 |
| Urinary System | p. 232 |
| Genital System | p. 243 |
| Head and Neck | p. 260 |
| Pharyngeal Arches | p. 262 |
| Pharyngeal Pouches | p. 266 |
| Pharyngeal Clefts | p. 268 |
| Molecular Regulation of Facial Development | p. 268 |
| Tongue | p. 273 |
| Thyroid Gland | p. 274 |
| Face | p. 275 |
| Intermaxillary Segment | p. 278 |
| Secondary Palate | p. 278 |
| Nasal Cavities | p. 282 |
| Teeth | p. 283 |
| Molecular Regulation of Tooth Development | p. 285 |
| Central Nervous System | p. 287 |
| Spinal Cord | p. 288 |
| Brain | p. 297 |
| Molecular Regulation of Brain Development | p. 308 |
| Cranial Nerves | p. 313 |
| Autonomic Nervous System | p. 315 |
| Ear | p. 321 |
| Internal Ear | p. 321 |
| Middle Ear | p. 324 |
| External Ear | p. 325 |
| Eye | p. 329 |
| Optic Cup and Lens Vesicle | p. 329 |
| Retina, Iris, and Ciliary Body | p. 331 |
| Lens | p. 333 |
| Choroid, Sclera, and Cornea | p. 333 |
| Vitreous Body | p. 333 |
| Optic Nerve | p. 334 |
| Molecular Regulation of Eye Development | p. 334 |
| Integumentary System | p. 339 |
| Skin | p. 339 |
| Hair | p. 341 |
| Sweat Glands | p. 342 |
| Mammary Glands | p. 342 |
| Appendix | p. 345 |
| Answers to Problems | p. 347 |
| Figure Credits | p. 357 |
| Glossary of Key Terms | p. 361 |
| Index | p. 371 |
| Table of Contents provided by Ingram. All Rights Reserved. |