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Intracellular Niches of Microbes : A Pathogens Guide Through the Host Cell
ISBN: 9783527322077 | 3527322078
Edition: 1stFormat: Hardcover
Publisher: Wiley-Blackwell
Pub. Date: 11/16/2009
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The book describes the different and exciting pathways which have been developed by pathogenic microbes to manage living inside host cells. It covers intracellular life styles of all relevant pathogenic but also symbiotic microorganisms with respect to the cell biology of the host-microbe interactions and the microbial adaptations for intracellular survival. It features intracellular trafficking pathways and characteristics of intracellular niches of individual microbes. The book also asks questions on the benefits for the microbe with regard t... MORE
| Introduction (Schaible and Haas) | |
| General chapters (each by an invited contributor) | |
| The evolution of intracellular microbes: from amoeba survivors to intracellular pathogens of mammals (Schaible and Haas) | |
| What's in it for a microbe and how does it adapt? (Schaible and Haas) | |
| Overview: Everybody has a home of their own (Haas) | |
| Gene transfer in evolution of intracellular parasitism | |
| ... MORE | |
| Cellular model systems to study phagosome biogenesis | |
| Toolbox: How to study phagosome maturation | |
| Phagosome-cytoskeleton interactions | |
| In vitro assays with phagosomes | |
| Intracellular expression profiling | |
| Proteomics and the biology of phagosome development | |
| Immunity to intracellular pathogens (Schaible) | |
| Consequences of compartmentation for therapeutic intervention (Schaible and Haas) | |
| Chapters on individual pathogens (each by an invited contributor) | |
| Intraphagosomal bacteria | |
| Afipia | |
| Brucella | |
| Burkholderia pseudomallei | |
| Chlamydia | |
| Coxiella | |
| Ehrlichia, Anaplasma | |
| Francisella | |
| Legionella pneumophila | |
| Mycobacterium marinum | |
| Mycobacterium tuberculosis vsMavium, Mbovis BCG, Mleprae | |
| Rhodococcus, Nocardia | |
| Salmonella | |
| Intracytoplasmic bacteria | |
| Listeria | |
| Rickettsia | |
| Shigella | |
| Intracellular symbionts | |
| Amoeba symbionts | |
| Wohlbachia | |
| Bacterial symbionts in plants | |
| Algal Symbionts | |
| Parasites and fungi | |
| Histoplasma | |
| Leishmania | |
| Plasmodium and Babesia | |
| Theileria | |
| Toxoplasma gondii | |
| Table of Contents provided by Publisher. All Rights Reserved. |
Ulrich Schaible is Professor of Immunology at London School of Hygiene & Tropical Medicine, UK. After graduating from Freiburg University, he obtained his PhD working with Marcus Simon at the Max-Planck-Institute of Immunobiology, Freiburg. After a postdoc with David Russell at Washington University, St. Louis, USA, he joined the department of Stefan Kaufmann at the Max-Planck-Institute of Infection Biology, Berlin. He combines immunology and cellular microbiology to study host-pathogen-interactions in tuberculosis. He has authored 86 articles and received the Royal Society Wolfsohn Research Merit Award, the GlaxoSmithKline-Foundation for Clinical-Research-Award and the Otto-Westphal-Award of the German Society of Immunology.
Albert Haas was appointed Professor of Cell Biology at Bonn University in 2001. After graduating from W++rzburg University, he obtained his PhD in Microbiology working with Werner Goebel on Listeria pathogenesis. After postdoctoral research in Bill Wickner's lab at UCLA (Los Angeles, CA) and Dartmouth College (Hanover, NH) on yeast cell biology, he returned to W++rzburg University to start his independent research which focuses on questions of phagosome biogenesis. He has authored 35 articles and received the Vector-Laboratories Young Investigator Award (American Society for Microbiology), the Butenandt-Habilitation-Award and the Karl-Lohmann-Award, both from the German Society for Biochemistry and Molecular Biology.
Albert Haas was appointed Professor of Cell Biology at Bonn University in 2001. After graduating from W++rzburg University, he obtained his PhD in Microbiology working with Werner Goebel on Listeria pathogenesis. After postdoctoral research in Bill Wickner's lab at UCLA (Los Angeles, CA) and Dartmouth College (Hanover, NH) on yeast cell biology, he returned to W++rzburg University to start his independent research which focuses on questions of phagosome biogenesis. He has authored 35 articles and received the Vector-Laboratories Young Investigator Award (American Society for Microbiology), the Butenandt-Habilitation-Award and the Karl-Lohmann-Award, both from the German Society for Biochemistry and Molecular Biology.
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