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Glencoe Basic Pharmacology

ISBN: 9780028046549 | 0028046544
Edition: 4th
Format: Paperback
Publisher: Career Education
Pub. Date: 10/26/1998

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SummaryTable of Contents
This text provides a basic understanding of pharmacology with an emphasis on drug therapy and drug interaction. In each section, a review of pertinent physiology and related diseases precedes the presentation of the pharmacology of the drugs. New to this edition: a chapter on drugs and the geriatric patient; information on nutrition and vitamins with explanations of drugs and food interactions; more thorough math review; new material on patient education and Internet activities.
PART I General Concepts1(56)
CHAPTER 1 INTRODUCTION TO PHARMACOLOGY
3(15)
Drug Sources
4(1)
... MORE
Terminology Related to Drug Effects
5(1)
Basic Concepts in Pharmacology
6(3)
Drug Safety
9(1)
Drug Momenclature
10(3)
Chapter Review
13(5)
CHAPTER 2 BIOLOGICAL FACTORS AFFECTING THE ACTION OF DRUGS
18(18)
Drug Forms
19(2)
Routes of Administration
21(1)
Drug Absorption
22(2)
Drug Distribution
24(1)
Drug Metabolism
25(1)
Drug Excretion
25(1)
Half-Life
26(1)
Blood Drug Levels
26(1)
Bioavailability
26(1)
Factors of Individual Variation
27(1)
Pediatric Drug Considerations
28(2)
Drug Interactions
30(1)
Terminology Associated With Chronic Drug Use and Abuse
31(1)
Chapter Review
32(4)
CHAPTER 3 GERIATRIC PHARMACOLOGY
36(10)
Drug Use in the Elderly
37(2)
Effects of Age on Drug Response
39(1)
Drug Compliance in the Elderly
40(2)
Chapter Review
42(4)
CHAPTER 4 MATH REVIEW AND DOSAGE CALCULATIONS
46(11)
Fractions, Decimals, and Percents
47(2)
Dosage Calculations
49(1)
Systems of Measurement
50(3)
Monitoring IV Infusion Rates
53(1)
Chapter Review
54(3)
PART II Pharmacology of the Peripheral Nervous System57(70)
CHAPTER 5 AUTONOMIC NERVOUS SYSTEM
59(9)
Nervous System Organization
60(1)
Physiology and Pharamacology
60(1)
Parasympathetic and Sympathetic Divisions
61(4)
Chapter Review
65(3)
CHAPTER 6 DRUGS AFFECTING THE SYMPATHETIC NERVOUS SYSTEM
68(16)
Adrenergic Nerve Endings
69(1)
Norepinephrine Versus Epinephrine
69(1)
Adrenergic Receptors
69(2)
Alpha-Adrenergic Drugs
71(1)
Beta-Adrenergic Drugs
72(2)
Dopamine
74(1)
Alpha-Adrenergic Blocking Drugs
74(1)
Beta-Adrenergic Blocking Drugs
75(2)
Adrenergic Neuronal Blocking Drugs
77(3)
Chapter Review
80(4)
CHAPTER 7 DRUGS AFFECTING THE PARASYMPATHETIC NERVOUS SYSTEM
84(13)
Parasympathetic System
85(1)
Chrolinergic Drugs
86(5)
Anticholinergic Drugs
91(3)
Chapter Review
94(3)
CHAPTER 8 DRUGS AFFECTING THE AUTONOMIC GANGLIA
97(6)
Ganglionic Drugs
98(2)
Chapter Review
100(3)
CHAPTER 9 SKELETAL MUSCLE RELAXANTS
103(13)
Clinical Indications
104(1)
Peripherally Acting Skeletal Muscle Relaxants
104(5)
Direct-Acting Skeletal Muscle Relaxants
109(1)
Centrally Acting Skeletal Muscle Relaxants
109(3)
Chapter Review
112(4)
CHAPTER 10 LOCAL ANESTHETICS
116(11)
Mechanism of Action
117(1)
Pharmacology
117(2)
Routes of Administration
119(1)
Adverse Effects
119(1)
Clinical Applications
119(5)
Chapter Review
124(3)
PART III Pharmacology of the Central Nervous System127(132)
CHAPTER 11 INTRODUCTION TO THE CENTRAL NERVOUS SYSTEM
129(7)
Parts of the Brain
130(3)
Functional Components
133(1)
Chapter Review
134(2)
CHAPTER 12 SEDATIVE-HYPNOTIC DRUGS AND ALCOHOL
136(15)
Sleep Cycle
137(1)
Barbiturate Sedatives and Hypnotics
138(4)
Miscellaneous Nonbarbiturates
142(1)
Benzodiazepines
142(1)
Alcohol
143(4)
Chapter Review
147(4)
CHAPTER 13 ANTIPSYCHOTIC AND ANTIANXIETY DRUGS
151(13)
Types of Mental Illness
152(1)
Antipsychotic Drugs
152(4)
Antianxiety Drugs
156(4)
Chapter Review
160(4)
CHAPTER 14 ANTIDEPRESSANTS, PSYCHOMOTOR STIMULANTS AND LITHIUM
164(12)
Types of Depression
165(1)
Drugs Used to Treat Depression
165(7)
Chapter Review
172(4)
CHAPTER 15 PSYCHOTOMIMETIC DRUGS OF ABUSE
176(14)
LSD-Type Hallucinogens
177(2)
Psychomotor Stimulants
179(4)
Miscellaneous Psychotomimetic Drugs
183(3)
Chapter Review
186(4)
CHAPTER 16 ANTIEPILEPTIC DRUGS
190(9)
Types of Epilepsy
191(1)
Drugs Used to Control Epilepsy
192(2)
Drugs Used in the Treatment of Absence Seizures
194(1)
Treatment of Status Epilepticus
195(1)
Use of Antiepileptic Drugs During Pregnancy
195(1)
Antiepileptic Drug Interactions
195(1)
Chapter Review
196(3)
CHAPTER 17 ANTIPARKINSON DRUGS
199(9)
Neurotransmitters Affecting the Basal Ganglia
200(1)
Drug Therapy
200(5)
Chapter Review
205(3)
CHAPTER 18 GENERAL ANESTHETICS
208(11)
General Anesthesia
209(2)
Use of General Anesthetics
211(6)
Chapter Review
217(2)
CHAPTER 19 NARCOTIC (OPIOLD) ANALGESICS
219(18)
Sources
220(2)
Site and Mechanism of Action
222(2)
Pharamacological Effects
224(4)
Absorption and Metabolism
228(1)
Adverse Effects
228(1)
Acute Narcotic Poisoning
229(1)
Narcotic Antagonists
229(2)
Special Considerations
231(1)
Drug Interactions
231(3)
Chapter Review
234(3)
CHAPTER 20 NONNARCOTIC ANALGESICS ANTI-INFLAMMATORY AND ANTIGOUT DRUGS
237(22)
Salicylates
240(3)
Acetaminophen
243(1)
Anti-Inflammatory Drugs
244(4)
Drugs Useful in Treating Gout
248(4)
Drug Interactions
252(2)
Chapter Review
254(5)
PART IV Pharmacology of the Heart259(36)
CHAPTER 21 CARDIAC PHYSIOLOGY AND PATHOLOGY
361(7)
Cardiac Function
262(1)
Main Diseases of the Heart
263(2)
Chapter Review
265(3)
CHAPTER 22 CARDIAC GLYCOSIDES AND THE TREATMENT OF CONGESTIVE HEART FAILURE
268(7)
Cardiac Glycosides
269(3)
Diuretic Therapy of CHF
272(1)
Chapter Review
273(2)
CHAPTER 23 ANTIARRHYTHMIC DRUGS
275(13)
Types of Arrhythmias
276(2)
Class 1 Antiarrhythmic Drugs
278(4)
Class 2 Antiarrhythmic Drugs
282(1)
Class 3 Antiarrhythmic Drugs
282(1)
Class 4 Antiarrhythmic Drugs
283(1)
Other Antiarrhythmic Drugs
284(1)
Special Considerations
284
Chapter Review
293
CHAPTER 24 ANTIANGINAL DRUGS
288(7)
Nitries and Nitrates
289(2)
Beta-Adrenergic Blocking Drugs
291(1)
Calcium Antagonists
291(1)
Clinical Indications for Antianginal Drugs
292(1)
Chapter Review
293(2)
PART V Pharmacology of the Vascular and Renal Systems295(92)
CHAPTER 25 DIURETICS
297(18)
Renal Physiology
298(3)
Conditions Associated With Renal Dysfunction
301(1)
Osmotic Diuretics
302(2)
Carbonic Anhydrase Inhibitors
304(1)
Thiazide and Thiazide-Like Diuretics
305(1)
Organic Acid Diuretics
306(2)
Potassium-Sparing Diuretics
308(1)
Miscellaneous Diuretics
308(1)
Special Considerations
308(1)
Drug Interactions and Incompatibilities
309(1)
Overdose
309(3)
Chapter Review
312(3)
CHAPTER 26 ANTIHYPERTENSIVE DRUGS
315(11)
Physiological Factors Controlling Blood Pressure
316(1)
Antihypertensive Therapy
317(6)
Chapter Review
323(3)
CHAPTER 27 ANTICOAGULANTS AND COAGULANTS
326(16)
Coagulation
327(1)
Anticoagulants
328(7)
Monitoring Coagulation
335(1)
Thrombolytic Enzymes
336(1)
Congulants/Hemostatics
337(2)
Chapter Review
339(3)
CHAPTER 28 NUTRITION AND THERAPY
342(18)
Nutrients
343(3)
Vitamins
346(1)
Fat-Soluble Vitamins
347(3)
Water-Soluble Vitamins
350(2)
Body Water
352(1)
Minerals
353(3)
Chapter Review
356(4)
CHAPTER 29 HYPOLIPIDEMIC DRUGS
360(12)
Liver Metabolism and Lipoproteins
361(2)
Monitoring Blood Lipid Levels
363(1)
Bile Acid Sequestrants
363(1)
HMG-CoA Reductase Inhibitors
364(2)
Miscellaneous Hypolipidemics
366(1)
Clinical Indications
367(1)
Contraindications
368(1)
Drug Interactions
368(2)
Chapter Review
370(2)
CHAPTER 30 ANTIANEMICS
372(15)
Causes of Anemia
373(1)
Iron Deficiency Anemia
374(2)
Cyanocobalamin Deficiency
376(2)
Folic Acid Deficiency
378(3)
Erythropoetin
381(2)
Chapter Review
383(4)
PART VI Drugs That Affect the Respiratory System387(26)
CHAPTER 31 ANTIALLERGIC AND ANTIHISTAMINIC DRUGS
389(14)
Action of Histamine
390(1)
Antiallergic Agents
391(2)
Antihistaminic Agents
393(7)
Chapter Review
400(3)
CHAPTER 32 BRONCHODILATOR DRUGS AND THE TREATMENT OF ASTHMA
403(10)
Respiratory Diseases
404(1)
Role of the Autonomic Nervous System
405(1)
Bronchodilator Drugs
406(3)
Antiallergic Agents
409(1)
Mucolytics
409(1)
Expectorants
410(1)
Chapter Review
410(3)
PART VII Pharmacology of the GI Tract413(44)
CHAPTER 33 THERAPY OF GASTROINTESTINAL DISORDERS: GERD, ULCERS, AND VOMITING
415(30)
Digestion and Ulcer Production
416(2)
Management of Ulcers
418(1)
Management of Gastroesophogeal Reflux Disease (GERD)
419(1)
Antisecretory Drugs
419(11)
Antacids
430(2)
Sucralfate
432(2)
Management of Emesis
434(7)
Chapter Review
441(4)
CHAPTER 34 AGENTS THAT AFFECT INTESTINAL MOTILITY
445(12)
Bowel Function
446(1)
Antidiarrheals
446(3)
Laxatives and Cathartics
449(4)
Chapter Review
453(4)
PART VIII Pharmacology of the Endocrine System457(92)
CHAPTER 35 INTRODUCTION TO THE ENDOCRINE SYSTEM
459(7)
Endocrine System
460(1)
Uses of Hormones
460(4)
Chapter Review
464(2)
CHAPTER 36 ADRENAL STEROIDS
466(14)
Glucocorticoids
467(5)
Mineralocorticoids
472(2)
Special Considerations
474(1)
Drug Interactions
475(2)
Chapter Review
477(3)
CHAPTER 37 GONADAL HORMONES AND THE ORAL CONTRACEPTIVES
480(24)
Female Sex Hormones
481(13)
Male Sex Hormones (Androgens)
494(3)
Impotence
497(3)
Chapter Review
500(4)
CHAPTER 38 DRUGS AFFECTING THE THYROID AND PARATHYROID GLANDS AND BONE DEGENERATION
504(16)
Thyroid Function, Pharmacology, and Disorders
505(6)
Parathyroid Hormones
511(5)
Chapter Review
516(4)
CHAPTER 39 PANCREATIC HORMONES AND ANTIDIABETIC DRUGS
520(20)
Pancreatic Endocrine Function
521(1)
Diabetes Mellitus
521(2)
Treatment of Diabetes
523(13)
Chapter Review
536(4)
CHAPTER 40 POSTERIOR PITUITARY HORMONES AND DRUGS AFFECTING UTERINE MUSCLE
540(9)
Diabetes Insipidus
541(1)
Drugs Affecting Uterine Muscle
542(1)
Tocolytics
543(2)
Chapter Review
545(4)
PART IX Pharmacology of Infections Diseases549(76)
CHAPTER 41 ANTIBACTERIAL AGENTS
551(18)
Morphology of Bacteria
552(1)
Chemotherapy
553(1)
Penicillins
554(3)
Cephalosporins
557(1)
Aminoglycosides
558(1)
Tetracyclines
559(2)
Sulfonamides
561(1)
Macrolide Antibiotics
562(1)
Fluroquinolone Antimicrobials
563(1)
Miscellaneous Antimicrobial Drugs
563(1)
Drugs Used to Treat Tuberculosis
564(1)
Chemoprophylaxis
565(1)
Chapter Review
565(4)
CHAPTER 42 ANTIFUNGAL AND ANTIVIRAL (AIDS) DRUGS
569(31)
Antinfungal Drugs
570(8)
Viral Diseases and Antiviral Drugs
578(3)
Antiviral Drugs
581(8)
Drug Interactions
589(6)
Chapter Review
595(5)
CHAPTER 43 ANTIPROTOZOAL AND ANTHELMINTIC DRUGS
600(16)
Protozoal Infections
601(1)
Malaria
601(4)
Dysentery
605(2)
Other Protozoal Infections
607(1)
Anthelmintic Drugs
608(4)
Chapter Review
612(4)
CHAPTER 44 ANTISEPTICS AND DISINFECTANTS
616(9)
Mechanism of Action
617(6)
Chapter Review
623(2)
PART X Antineoplastics and Drugs Affecting the Immune System625
CHAPTER 45 ANTINEOPLASTIC AGENTS
627(11)
Types of Cancer
628(1)
Alkylating Drugs
629(1)
Antimetabolites
630(1)
Miscellaneous Antineoplastic Drugs
631(3)
Chapter Review
634(4)
CHAPTER 46 IMMUNOPHARMACOLOGY
638
Immune System
639(1)
Immunosuppressive Drugs
640(3)
Immunostimulant Drugs
643(1)
Chapter Review
644

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