9780781735148

The defining reference work in immunology today is now available in an entirely new text! This edition places greater emphasis on molecular mechanisms underlying cellular function and physiology, and includes outstanding new chapters on neuroimmunology and immunotherapy...completely updated coverage of immune suppression and regulatory T cells...and new and expanded chapters on lymphocytes, the immunology of aging, autoimmunity, and more. A free CD-ROM provides one-click access to all of the content and illustrations from the text--plus Internet links to PubMed and 50 other sites. "Nothing else competes with it."--JAMA, review of the previous edition

Introduction
The Immune System
History of Immunology Immunoglobulins and B Lymphocytes
Immunoglobulins: Structure & Function
Antigen-Antibody Interactions and Monoclonal Antibodies
Immunoglobulins: Molecular Genetics
B Lymphocyte Development and Biology
B Lymphocyte Signaling Mechanisms and Activation T Cells & NK Cells
T cell antigen receptor genes
T-Cell Developmental Biology
Peripheral T Lymphocyte Responses and Function
T Lymphocyte Activation
NK Cells
Accessory Molecules and Co-Stimulation Organization and Evolution of the Immune System
Lymphoid Tissues & Organs
Dendritic Cells
Macrophages and the Immune Response
Innate Immune System
Evolution of the Immune System Antigen Processing and Presentation
The Major Histocompatibility Complex and its Proteins
The Biochemistry and Cell Biology of Antigen Processing Regulation of the Immune Response
Immunogenicity and Antigen Structure
Fc Receptors
Type I Cytokines and Interferons
TNF Family Cytokines
Immunoglobulins Super Family Cytokines
Chemokines
Programmed Cell Death
Immunologic Memory
Immunological Tolerance
Immune Suppression & Regulatory T Cells
The Mucosal Immune System
Neural Immune Interactions in Health and Disease
Immunology of Aging Effector Mechanisms of Immunity
Complement
Phagocytosis
Cytotoxic T Lymphocytes
Inflammation Immunity to Infectious Agents
The Immune Response to Parasites
Viral Immunology
Immunity to Intracellular Bacteria
Immunity to Extracellular Bacteria
Immunology of HIV Infection
Vaccines Immunologic Mechanisms in Disease
Systemic Autoimmunity
Organ Specific Autoimmunity
Allergy
Transplantation Immunology
Tumor Immunology
Primary Immunodeficiency Diseases
Immunotherapy
Table of Contents provided by Publisher. All Rights Reserved.

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Fundamental Immunology

Fundamental Immunology

0781735149

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Table of Contents

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