The steady flow of new pharmaceuticals and new technology has provided clinicians with an arsenal of effective treatments and diagnostic techniques. However, these interventions come at a price. With healthcare providers continuing to struggle with rising costs, clinical effectiveness alone will no longer be the only criteria for evaluating a drug or device. In the face of limited budgets, healthcare payers and providers will be expected to Understand The value of new interventions in terms of economic, clinical, and quality of life benefits. Based on the core principles of pharmacoeconomics, this text provides an overview of the methodologies that can be applied to both drug and non-drug interventions.  Economic Evaluation in U.S. Health Care: Principles and Applications  offers health professionals a solid foundation for understanding, interpreting, and applying the tools of economic evaluation and is essential for anyone involved in healthcare decision-making.