Edited by
Ron Waksman, MD, FACC
Division of Cardiology, MedStar Washington Hospital Center, Washington, DC, USA

Shigeru Saito, MD, FACC, FSCAI, FJCC
Cardiology & Catheterization Laboratories, Shonan Kamakura General Hospital, Kamakura, Japan

Foreword, xi

Preface, xii

Part I Pathology, Indications, and Review of Clinical Trials

1 The pathobiology of CTO, 3
Sergey Yalonetsky, Azriel B. Osherov & Bradley H. Strauss

2 Collateral circulation in CTO, 9
Alfredo R. Galassi, S.D. Tomasello & Hazem Khamis

3 CTO: review of trials, 18
Tina L. Pinto Slottow & Ron Waksman

4 CTO-percutaneous coronary intervention: what is the evidence?, 26
Gabriel Maluenda, Tina L. Pinto Slottow & Ron Waksman

5 Case selection and long-term benefits, 33
Imran N. Ahmad, Kamran I. Muhammad & Patrick L. Whitlow

Part II Imaging

6 CT angiography: application in chronic total occlusions, 45
Hidehiko Hara, John R. Lesser, Nicholas Burke & Robert S. Schwartz

7 Co-registration CTO and CT angiography, 51
Gary M. Idelchik & Ariel Roguin

8 Optical coherence tomography to guide the treatment of chronic total occlusions, 60
Nicola Viceconte, Rodrigo Teijeiro-Mestre, Nicolas Foin, Alistair C. Lindsay and Carlo Di Mario.

9 IVUS-guided CTO-PCI, 67
Masashi Kimura & Yasushi Asakura

10 IVUS evaluation of CTO, 78
Akiko Maehara, Masahiko Ochiai & Gary S. Mintz

11 Magnetic navigation wire, 85
Steve Ramcharitar & Patrick Serruys

Part III Wires Technology

12 Deflecting wire systems, 93
Mirko Schiemann

13 Asahi wires, 97
Shigeru Saito

14 IVUS-guided recanalization of CTO, 105
Etsuo Tsuchikane

15 Frontrunner CTO technology, 109
Chad Kliger, Steven P. Sedlis & Jeffrey D. Lorin

16 Channel dilator: Corsair, 113
Masashi Kimura

Part IV Wires Technique

17 Tornus catheter, 121
Hideaki Kaneda

18 Antegrade approach: step by step, 126
Nicolaus Reifart

19 Use of two wires in the treatment of CTO, 134
Yves Louvard, Thierry Lefèvre & Marie-Claude Morice

20 Parallel-wire techniques, 143
Sudhir Rathore & Takahiko Suzuki

21 Guidewire handling techniques for CTO lesions, 147
Shigeru Saito

22 Subintimal angioplasty in coronary CTO, 155
Philippe Généreux & George D. Dangas

23 Antegrade device assisted re-entry techniques, 162
Nicolaus Reifart

24 The microchannel technique, 166
Mauro Carlino, Gill L. Buchanan & Cosmo Godino

25 The STAR technique, 172
Cosmo Godino, Mauro Carlino & Antonio Colombo

26 Attempting CTO after first failed attempt, 178
Sudhir Rathore & Takahiko Suzuki

27 Transradial approach for CTO lesions and tapered-tip guidewires, 184
Shigeru Saito

28 Bilateral approach, 191
Osamu Katoh

29 Tips and tricks of the CART technique, 198
Osamu Katoh

Part V Devices Technology

30 Recanalizing total occlusion in the periphery: utilization of radio frequency and other technology, 209
Shishir Murarka & Richard Heuser

31 High-frequency mechanical revascularization, 226
Eberhard Grube & Lutz Buellesfeld

32 Debulking of CTO, 230
Etsuo Tsuchikane

33 Vibrational angioplasty, 235
Lampros K. Michalis

34 Treatment of chronic total coronary occlusions with drug-eluting stents: overview of angiographic and clinical outcomes, 240
David E. Kandzari

35 Laser for CTO recanalization, 251
On Topaz

36 The ENABLER-P: a novel CTO crossing cystem, 257
Maurice Buchbinder

37 Collagenase plaque digestion for facilitating guidewire crossing, 262
Azriel B. Osherov & Bradley H. Strauss

38 The BridgePoint re-entry system, 268
Imran N. Ahmad, Kamran I. Muhammad & Patrick L. Whitlow

Part VI Complications

39 Complications during the retrograde approach for CTO, 275
Shigeru Saito

40 CTO: how to minimize contrast nephropathy, 279
Travis J. Bench & Luis Gruberg

Part VII Interesting Cases

41 Interesting cases I–VI, 291
Shigeru Saito

Index, 301

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