9781439872109

Toxicologic Pathology: Nonclinical Safety Assessment

  • ISBN 13:

    9781439872109

  • ISBN 10:

    1439872104

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 04/09/2013
  • Publisher: CRC Press

Note: Not guaranteed to come with supplemental materials (access cards, study guides, lab manuals, CDs, etc.)

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Summary

Designed to provide practical information for the bench toxicologic pathologist working in pharmaceutical drug research, this book presents histopathologic descriptions of lesions noted in drug development. Each section contains information related to the lesion to assist the pathologist in making a determination of the origin of the lesion, the importance of the lesion, and the relevance for assessing human risk. Organ-based chapters include a description of light microscopic and electron microscopic of pathological lesions, differential diagnoses, and biological consequences, pathogenesis and/or mechanism of lesion formation, and expected clinical pathology correlates.

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