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Based on a paradox that all things are poisons at certain doses, and the difference between poison and remedy is quantity, the determination of safe dosage forms the basis and focus of modern toxicology. Written by a team of experts, with new Editors joining Dr Hayes, this sixth edition discusses basic toxicological principles, toxic agents, target organ toxicity, testing methods and international regulatory requirements. With new chapters covering advancements in nanotechnology and all chapters updated to reflect the changing pace of research, an online version available as standard this edition is something no toxicologist should be without!