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Perinatal Stem Cells, 2nd Edition builds on the first edition to provide an updated tutorial on perinatal stem cells, including stem cells harvested from the amniotic fluid, placenta, maternal blood supply, umbilical cord and Wharton's Jelly. As in the first edition, coverage includes the underlying biology of each of the sources of pregnancy related stem cells, cell culture, and potential therapeutic uses, as well as insights on the impact of these stem cells from obstetricians and gynecologists, cardiologists, hematologists, tissue engineers, and cord blood bankers. Normally discarded as medical waste, perinatal stem cells offer a powerful therapeutic tool box alternative to the controversial embryonic stem cells. Since publication of the first edition, a burgeoning commerical industry has developed around various sources of perinatal cells, and the second edition now includes an overview of this growing industry. With contributions from some of the top academic stem cell laboratories in the United States as well as new chapters from international stem cell scientists, Perinatal Stem Cells presents and update on the cutting-edge research in the field while maintaining its signature clinical focus.
Table of Contents
List of Contributors
1. Amniotic Fluid Stem Cells Sean Vincent Murphy and Anthony Atala
2. Cord Blood Transplants: Perinatal Stem Cells in Clinical Practice Richard L. Haspel and Karen K. Ballen
3. Hematopoietic Stem Cell Development in the Placenta Katrin E. Rhodes, Akanksha Chhabra and Hanna K.A. Mikkola
4. Perinatal Mesenchymal Stem Cell Banking for Umbilical Cord Blood Transplantation and Regenerative Medicine Rouzbeh R. Taghizadeh
5. Making Organ and Stem Cell Transplantation Safer: The Role of Mesenchymal Stem Cells Hans Klingemann
6. Wharton?s Jelly Mesenchymal Stem Cells and Immune Modulation: Regenerative Medicine Meets Tissue Repair Rita Anzalone, Felicia Farina, Melania Lo Iacono, Simona Corrao, Tiziana Corsello, Giovanni Zummo, and Giampiero La Rocca
7. Immungenicity Vs. Immunomodulation of Perinatal Stem Cells Bram Lutton and Raimon Duran-Struuck
8. The Translational Potential of Perinatal Stem Cells in Clinical Medicine: Mesenchymal Stem Cells Radbeh Torabi, Vincenzo Villani, Christopher A. Mallard, and Curtis L. Cetrulo, Jr.
9. Newborn Stem Cells ? Identity, Function and Clinical Potential Anthony Park, Ann Chidgey, Sean Murphy, Ursula Manuelpillai and Richard Boyd
10. Biomedical Potential of Human Perinatal Stem Cells Oleg V. Semenov and Christian Breymann
11. Progenitor Cell Therapy for the Treatment of the Traumatic Brain Injury Alex Bryan Olsen, Robert A. Hetz, Supinder S. Bedi, and Charles S. Cox, Jr.
12. The Human Amniotic Membrane: A Tissue with Multifaceted Properties and Different Potential Clinical Applications Maddalena Caruso, Antonietta Silini, and Ornella Parolini
13. Advances and Possibile Applications of Human Amnion for the Management of Liver Disease Fabio Marongiu, Marc C. Hansel, Kristen J. Skvorak, Maria Paola Serra, Marcella Sini, Roberto Gramignoli, Ezio Laconi and Stephen C. Strom
14. Amnion-Derived Cells for Stroke Restorative Therapy Loren E. Glover, Naoki Tajiri and Cesar V. Borlongan
15. Pregnancy-Acquired Fetal Progenitors as Natural Cell Therapy Elke Seppanen, Nicholas Fisk, and Kiarash Khosrotehrani
16. Perinatal Stem Cells ? An Industry Perspective Kyle J. Cetrulo
17. Patent Protection of Stem Cell Innovations: The Role of Patents in Commercialization John R. Wetherell
18. Interview with Frances Verter ? Founder of Parent?s Guide to Cord Blood Foundation Frances Verter and Kyle J. Cetrulo
19. Umbilical Cord Blood Banking: An Obstetricians Perspective Jordan H. Perlow