Kathleen Wagner, EdD, MSN, RN, is now faculty emerita, having recently retired from the University of Kentucky College of Nursing after many years of teaching pathophysiology, pathopharmacology, and high-acuity nursing to undergraduate nursing students. She was also the educational consultant for the Undergraduate Nursing Program at the University of Kentucky. She has a doctorate in instructional systems design and continues to work on a team developing web-based clinical simulations for nursing students.

Melanie Hardin-Pierce, DNP, RN, APRN, ACNP-BC, is a tenured associate professor in the University of Kentucky College of Nursing, where she has over 30 years of experience as a critical care nurse and has taught high-acuity nursing to undergraduate and graduate nursing students. She currently teaches in the Doctor of Nursing Practice program and is the Coordinator of the Adult Geriatric Acute Care Nurse Practitioner DNP Option. In addition to teaching, she has been active in curriculum development in both baccalaureate and graduate nursing programs. She earned her Doctor of Nursing Practice degree at the University of Kentucky, having studied oral health in mechanically ventilated patients. She is a board-certified acute care nurse practitioner who practices as a critical care intensivist in the Veterans Health Administration Medical Center, Cooper Drive Division, Lexington. She is active in research of critically ill, mechanically ventilated patients; evidence-based practice; and interdisciplinary collaboration.

Darlene Welsh, PhD, MSN, RN, is Associate Professor, BSN Program Director, and Assistant Dean of Undergraduate Faculty Affairs at the University of Kentucky College of Nursing. Dr. Welsh earned a PhD in Educational Psychology and an MS in Nursing from the University of Kentucky. Her experiences in the care of critically ill patients include direct patient care, the conduct of research, and supervision of undergraduate and graduate students. Her research interests center on the provision of dietary instruction for patients with heart failure and interprofessional education for clinicians.

PART 1: INTRODUCTION TO HIGH-ACUITY NURSING
1. High-Acuity Nursing
2. Holistic Care of the Patient and Family
3. Palliative and End-of-life Care
4. The Older Adult High-Acuity Patient

PART 2: THERAPEUTIC SUPPORT OF THE HIGH-ACUITY PATIENT
5. Acute Pain Management
6. Nutrition Support
7. Mechanical Ventilation
8. Basic Hemodynamic Monitoring
9. Basic Cardiac Rhythm Monitoring
10. Complex Wound Management

PART 3: PULMONARY
11. Determinants and Assessment of Pulmonary Function
12. Alterations in Pulmonary Function

PART 4: CARDIOVASCULAR
13. Determinants and Assessment of Cardiac Function
14. Alterations in Cardiac Function
15. Alterations in Myocardial Tissue Perfusion

PART 5: NEUROLOGIC
16. Determinants and Assessment of Cerebral Function
17. Mentation and Sensory Motor Complications of Acute Illness
18. Acute Stroke Injury
19. Traumatic Brain Injury
20. Acute Spinal Cord Injury

PART 6: GASTROINTESTINAL
21. Determinants and Assessment of Gastrointestinal Function
22. Alterations in Gastrointestinal Function
23. Alterations in Liver Function
24. Alterations in Pancreatic Function

PART 7: FLUID AND ELECTROLYTES
25. Determinants and Assessment of Fluid and Electrolyte Balance
26. Alterations in Fluid and Electrolyte Balance
27. Alterations in Kidney Function

PART 8: HEMATOLOGIC
28. Determinants and Assessment of Hematologic Function
29. Alterations in Red Blood Cell Function and Hemostasis
30. Alterations in White Blood Cell Function and Oncologic Emergencies

PART 9: NUTRITION AND METABOLISM
31. Determinants and Assessment of Nutrition and Metabolic Function
32. Metabolic Response to Stress
33. Diabetic Crises

PART 10: MULTISYSTEM DYSFUNCTION
34. Determinants and Assessment of Oxygenation
35. Multiple Trauma
36. Acute Burn Injury
37. Shock States
38. Multiple Organ Dysfunction Syndrome
39. Solid Organ and Hematopoietic Stem Cell Transplantation

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