The monumental Ghent altarpiece by the brothers Van Eyck is undoubtedly considered one of the main works of European art history. Since its completion in 1432, the Ghent altarpiece has attracted attention and interest over centuries. It has been a model for other painters, it has been praised by writers, and it has been copied in natural size. This publication offers the first overall view of all aspects of the Ghent altarpiece from its establishment and preservation to its reception and lasting influence.