Approximately 100,000 individuals have now obtained personal genomic profiles from direct-to-consumer services, and rapid advances in high-throughput genome sequencing technologies foreshadow a near-future in which millions of individuals will gain affordable access to their complete genome sequence. Personal genomics is an important component of the inevitable transition towards personalized medicine, as the medical establishment begins to explore and evaluatethe role of personal genomics in health and medicine. However there is currently there is very little training available for medical practitioners. This book provides a novel inquiry-based approach to understanding and interpreting the practical, medical, and societal aspects of personal genomicinformation. It opens with an introduction to genomics and the issues surrounding the use of genomic data, and then discusses the potential applications of this data using real examples and data sets.