9783527322756

Written by leading experts in the field as part of an interdisciplinary pan-European research program funded by the EU, this book provides a unique and comprehensive overview of how microarray technology can be used in safely tracking the most highly dangerous pathogens. A must-have for public health agencies focused on bioterrorism as well as all laboratories working with BSL3 and/or BSL 4 agents.

Tania Kostic is a researcher in the Department of Bioresources/Microbiology at the Austrian Research Centers at Seibersdorf working on microbial diagnostic microarrays.

Patrick Butaye is a veterinary researcher at the Veterinary and Agrochemical Research Center in Brussels with a focus on antimicrobial resistance in bacteria from animal origin.

Jacques Schrenzel is a physician and microbiologist, heading the central bacteriological laboratory of the Hopitaux Universitaires de Geneve. He is also a consultant for infectious diseases and is in charge of the genome research laboratory.

Preface
Introduction on Microarray-based Detection Methods
Methods
Long-oligonucleotide Microarray-based Microbial Detection
Sequence-specific End-labelling of Oligonucleotides (SSELO)
Non-cognate Approaches for Pathogen Detection on Microarrays
Patterning Techniques for Array Platforms
Probe Immobilization Techniques in Array Technologies
Identification
Low-Cost-and-Density (LCD)-Microarrays - a Novel Technique for Identification and Typing of Microorganisms
DNA Microarray Technique for Detection and Identification of Viruses Causing Encephalitis and Hemorrhagic Fever
Microarrays for genomotyping of pathogens
Typing
Single Nucleotide Polymorphisms (SNPs) as Targets for DNA-array Based Identification and Typing of BSL3 Bacteria
Use of a Microchip to Detect Antibiotic Resistance Genes in Bacillus anthracis
Quality Control
Progress Toward Development of Microarrays for Routine Diagnostic Use for Detection of Select High Risk Pathogens
Table of Contents provided by Publisher. All Rights Reserved.

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Detection of Highly Dangerous Pathogens

Detection of Highly Dangerous Pathogens

3527322752

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