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Clinical Research in Oral Health surveys the essentials of clinical research in oral health, anchoring these principles within the specific context of the oral health arena. Addressing research questions exclusively applicable to dentistry and oral health, the book thoroughly illustrates the principles and practice of oral health clinical research. Clinical Research in Oral Health also clarifies the framework of regulatory issues and presents emerging concepts in clinical translation, relating the research principles to clinical improvement.
William V. Giannobile is a William K. & Mary Anne Najjar Endowed Professor of Dentistry and Biomedical Engineering at the University of Michigan. He is also the Director of the Michigan Center for Oral Health Research and an Associate Editor of the Journal of Periodontology.
Robert J. Genco is a State University of New York Distinguished Professor of Oral Biology, and Microbiology, and Immunology at the University at Buffalo. He is also the Vice Provost and Director of the University at Buffalo Office of Science, Technology Transfer and Economic Outreach, and Editor-in-Chief Emeritus of the Journal of Periodontology.
Brian A. Burt is Professor Emeritus, Department of Epidemiology, and formerly the Director, Program in Dental Public Health, School of Public Health; and Professor Emeritus, School of Dentistry, University of Michigan, Ann Arbor, MI. He was editor of the journal Community Dentistry and Oral Epidemiology from 1997 to 2007.
Table of Contents
Clinical and Translational Research: Implications in the Promotion of Oral Health
Ethics in Oral Health Research
Responsibilities of Institutions and Individuals in Clinical Research in the Oral Health Sciences
Regulatory Process for the Evaluation of Dental Drugs, Devices and Biologics
Clinical and Translational Research Grantsmanship: Funding Opportunities and Obtaining Research Support
Data Management in Oral Health Research
Hypothesis Testing and Avoiding False-Positive Conclusions
Outcomes in Oral Health Research
Examiner Training: Standardization and Calibration in Periodontal Studies
Observational Studies in Oral Health Research
Initial Clinical Trials Allow Assessment of Safety, Dosing and Preliminary Efficacy Prior to Large Randomized Controlled Pivotal Studies
Phase III Pivotal Clinical Trials: Clinical Decision-making
Dental Practice-Based Research Networks
The Technology Transfer Process for Life Science Innovations in Academic Institutions
Adoption of New Technologies for Clinical Practice
Publication of Research Findings
The Evidence-base for Oral Health
Table of Contents provided by Publisher. All Rights Reserved.