This volume presents the proceedings of the13th International Conference on Biomedical Engineering (ICBME2008), help from the 3rd to 6th December 2008 in Singapore. The presented papers reflect the broad scope of the conference including topics like:Artificial Organs, Bioengineering Education, Bioinformatics and Digital Medicine, Biomaterials, Biomechanics, Biomedical Imaging, Biomedical Instrumentation, Biosensors, BioMEMs and Lab-on-Chip, Biosignal Processing, Cardiovascular Bioengineering, Cell and Biomolecular Mechanics, Cellular and Biomolecular Engineering, Clinical Engineering, Computational Bioengineering, Computer-Integrated and Computer-Assisted Surgery, Controlled Drug Delivery, Mechanobiology, Medical Robotics, Micro Nano Biomedical devices and systems, Nanobiotechnology, Neural Systems Engineering, Orthopaedics, Prosthetics and Orthotics, Rehabilitation Engineering and Assistive Technology, Pharmaceutical Sciences and Engineering, Physiological System Modeling, Regenerative Medicine and Tissue Engineering, Telemedicine and Healthcare.