The "essential" companion to the landmark Users' Guides to the Medical Literature - completely revised and updated! Evidence-based medicine involves the careful interpretation of medical studies and its clinical application. And no resource helps you do it better-and faster-than Users' Guides to the Medical Literature: Essentials of Evidence-Based Clinical Practice. This streamlined reference distills the most clinically-relevant coverage from the parent Users' Guide into a one highly-focused, portable resource. Praised for its clear explanations of detailed statistical and mathematical principles, The Essentials concisely covers both basic and advanced concepts in using evidence-based medicine-everything you need to deliver optimal patient care.