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| List of Contributors | |
| Preface to the Fourth Edition | |
| Foreword | |
| List of Abbreviations | |
| Diabetes in its Historical and Social Context | |
| The History of Diabetes Mellitus | |
| The Classifi cation and Diagnosis of Diabetes | |
| Epidemiology of Type 1 Diabetes | |
| Epidemiology of Type 2 Diabetes | |
| The Global Burden of Diabetes | ... MORE|
| Normal Physiology | |
| Islet Function and Insulin Secretion | |
| Insulin Action | |
| Control of Weight: How Do We Get Fat? | |
| Pathogenesis of Diabetes | |
| Type 1 Diabetes | |
| Autoimmune Type 1 Diabetes | |
| Other Disorders with Type 1 Phenotype | |
| Abnormalities of Insulin Secretion and ß-Cell Defects in Type 2 Diabetes | |
| Insulin Resistance in Type 2 Diabetes | |
| The Genetics of Type 2 Diabetes: From Candidate Gene Biology to Genome-Wide Studies | |
| Metabolic Disturbances in Diabetes | |
| Obesity and Diabetes | |
| Other Types of Diabetes | |
| Monogenic Causes of Diabetes | |
| Drug-Induced Diabetes | |
| Endocrine Disorders that Cause Diabetes | |
| Pancreatic Diseases and Diabetes | |
| Managing the Patient with Diabetes | |
| Clinical Presentations of Diabetes | |
| The Aims of Diabetes Care | |
| Educating the Patient with Diabetes | |
| Lifestyle Issues: Diet | |
| Lifestyle Issues: Exercise | |
| Social Aspects of Diabetes | |
| Monitoring Diabetes | |
| Drug Therapy: Special Considerations in Diabetes | |
| Treatment of Diabetes | |
| Insulin and Insulin Treatment | |
| New Technologies for Insulin Administration and Glucose Monitoring | |
| Oral Antidiabetic Agents | |
| Non-Insulin Parenteral Therapies | |
| How to Use Type 2 Diabetes Treatments in Clinical Practice: Combination Therapies | |
| In-Hospital Treatment and Surgery in Patients with Diabetes | |
| Hypoglycemia in Diabetes | |
| Acute Metabolic Complications of Diabetes: Diabetic Ketoacidosis and Hyperosmolar Hyperglycemia | |
| Microvascular Complications in Diabetes | |
| Pathogenesis of Microvascular Complications | |
| Diabetic Retinopathy | |
| Diabetic Nephropathy | |
| Diabetic Peripheral Neuropathy | |
| Macrovascular Complications in Diabetes | |
| The Pathogenesis of Macrovascular Complications Including Atherosclerosis in Diabetes | |
| Cardiovascular Risk Factors | |
| Hypertension | |
| Dyslipidemia: Diabetes Lipid Therapies | |
| Congestive Heart Failure | |
| Cerebrovascular Disease | |
| Peripheral Vascular Disease | |
| Other Complications of Diabetes | |
| Foot Problems in Patients with Diabetes | |
| Sexual Function in Men and Woman with Diabetes | |
| Gastrointestinal Manifestations of Diabetes | |
| The Skin in Diabetes | |
| Bone and Rheumatic Disorders in Diabetes | |
| Psychologic Factors and Diabetes | |
| Diabetes and Infections | |
| Diabetes in Special Groups | |
| Diabetes in Childhood | |
| Diabetes in Adolescence and Transitional Care | |
| Diabetes in Pregnancy | |
| Diabetes in Old Age | |
| Psychiatric Disorders and Diabetes | |
| Delivery and Organization of Diabetes Care | |
| The Role of Community and Specialist Services | |
| The Role of the Multidisciplinary Team | |
| Models of Diabetes Care Across Different Resource Settings | |
| Future Directions | |
| Future Drug Treatment for Type 1 Diabetes | |
| Future Drug Treatments for Type 2 Diabetes | |
| Other Future Directions | |
| Stem Cell Therapy in Diabetes | |
| Islet Transplantation | |
| Gene Therapy | |
| Future Models of Diabetes Care | |
| Index | |
| Table of Contents provided by Publisher. All Rights Reserved. |
Clive S. Cockram, MB BS, BSc, MD (Lond), FRCP, FRACP, FHKAM (Med)
Emeritus Professor of Medicine, Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China
Allan Flyvbjerg, MD, DMSc
Professor of Clinical Endocrinology and Chair, Department of Endocrinology and Internal Medicine, The Medical Research Laboratories, Aarhus University Hospital - Aarhus University, Aarhus, Denmark
Barry J. Goldstein, MD, PhD, FACP, FACE
Therapeutic Area Head, Diabetes and Obesity, Vice President, Clinical Research, Metabolism, Merck Research Laboratories, Rahway, NJ, USA