This is the second edition of the successful textbook written by the prize-winning scientist Andreas Ziegler, former President of the German Region of the International Biometric Society, and Inke R. Konig, who has been teaching the subject over many years.The book gives a comprehensive introduction into the relevant statistical methods in genetic epidemiology. The second edition is thoroughly revised, partly rewritten and includes new chapters on traditional family studies and state-of-the-art genome-wide association studies. The book is ideally suited for advanced students in epidemiology, genetics, statistics, bioinformatics and biomathematics. Like in the first edition, the book contains many problems and solutions. E-learning Platform Edition: The paperback version of this book exclusively comes with an e-learning course created by Friedrich Pahlke. This e-learning course has been developed to complement the book and both provide a unique support tool for teaching the subject.