The expanded Second Edition of this acclaimed volume is the most comprehensive and cohesive text on the principles and methods of contemporary epidemiologic research. Coauthored by two leading epidemiologists, with 15 additional contributors, the Second Edition provides broader coverage than Dr. Rothman's single-authored original edition. A new section covers specific research areas--infectious diseases, ecologic studies, disease surveillance, analysis of vital statistics, screening, and clinical, environmental/occupational, reproductive/perinatal, genetic, and nutritional epidemiology.