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Medical Microbiology : Jawtz, Melnick and Adelberg's Medical Microbiology

ISBN: 9780838563168 | 0838563163
Edition: 21st
Format: Paperback
Publisher: McGraw Hill (Tx)
Pub. Date: 3/1/1998

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SummaryTable of Contents
A landmark revision of this classic, the 21st edition now reflects the new concepts in microbiology, immunology, bacteriology, mycology, parasitology, and virology. Updated information on HIV/AIDS has also been added.
Prefaceix
I. FUNDAMENTALS OF MICROBIOLOGY1(109)
1. The Science of Microbiology
1(6)
... MORE
Biologic Principles Illustrated by Microbiology
1(1)
Viruses
1(1)
Prions
2(1)
Prokaryotes
2(2)
Protists
4(3)
2. Cell Structure
7(31)
Optical Methods
7(1)
Eukaryotic Cell Structure
8(3)
Prokaryotic Cell Structure
11(23)
Staining
34(1)
Morphologic Changes During Growth
35(3)
3. Classification of Bacteria
38(9)
Definitions
38(1)
Criteria for Classification of Bacteria
38(1)
Identification & Classification Systems
39(1)
Description of the Major Categories & Groups of Bacteria
40(5)
Nonculture Methods for the Identification of Pathogenic Microoganisms
45(2)
4. The Growth, Survival, & Death of Microorganisms
47(9)
Survival of Microorganisms in the Natural Environment
47(1)
The Meaning of Growth
47(1)
Exponential Growth
48(1)
The Growth Curve
49(1)
Maintenance of Cells in the Exponential Phase
50(1)
Definition & Measurement of Death
50(2)
Antimicrobial Agents
52(4)
5. Cultivation of Microorganisms
56(8)
Requirements for Growth
56(1)
Sources of Metabolic Energy
56(1)
Nutrition
57(2)
Environmental Factors Affecting Growth
59(2)
Cultivation Methods
61(3)
6. Microbial Metabolism
64(26)
Role of Metabolism in Biosynthesis & Growth
64(2)
Focal Metabolites & Their Interconversion
66(4)
Assimilatory Pathways
70(4)
Biosynthetic Pathways
74(3)
Patterns of Microbial Energy-Yielding Metabolism
77(7)
Regulation of Metabolic Pathways
84(6)
7. Microbial Genetics
90(20)
Organization of Genes
90(3)
Replication
93(2)
Transfer of DNA
95(2)
Mutation & Gene Rearrangement
97(1)
Gene Expression
98(3)
Genetic Engineering
101(1)
Preparation of DNA Fragments With Restriction Enzymes
101(1)
Physical Separation of Differently Sized DNA Fragments
101(1)
Cloning of DNA Restriction Fragments
101(3)
Characterization of Cloned DNA
104(1)
Site-Directed Mutagenesis
105(1)
Analysis With Cloned DNA: Hybridization Probes
105(2)
Manipulation of Cloned DNA
107(1)
Recombinant Strains in the Environment
107(3)
II. IMMUNOLOGY110(24)
8. Immunology (Roderick Nairn, PhD)
110(24)
Immunity & the Immune Response
110(1)
Mechanisms of Nonspecific Host Defense
110(6)
Mechanisms of Specific Host Defense
116(1)
Antigen Recognition Molecules
117(1)
Antibodies (Immunoglobulins)
117(4)
Cell Surface Receptors for Antigen
121(3)
Antibody-Mediated (Humoral) Immunity
124(2)
The Complement System
126(1)
Cell-Mediated Immunity
127(2)
Cytokines
129(1)
Hypersensitivity
129(2)
Inadequate Immune Responses to Infectious Agents
131(1)
Immunologic Techniques: In Vitro Antigen-Antibody Reactions
132(2)
III. BACTERIOLOGY134(185)
9. Pathogenesis of Bacterial Infection
134(10)
Identifying Bacteria That Cause Disease
134(2)
Transmission of Infection
136(1)
The Infectious Process
136(1)
The Clonal Nature of Bacterial Pathogens
137(1)
Regulation of Bacterial Virulence Factors
137(1)
Bacterial Virulence Factors
138(7)
10. Antimicrobial Chemotherapy
145(32)
Mechanisms of Action of Clinically Used Antimicrobial Drugs
145(3)
Resistance to Antimicrobial Drugs
148(3)
Antimicrobial Activity in Vitro
151(1)
Antimicrobial Activity in Vivo
152(2)
Clinical Use of Antibiotics
154(3)
Disinfectants
157(1)
Antimicrobial Drugs for Systemic Administration
158(19)
11. Normal Microbial Flora of the Human Body
177(5)
Role of the Resident Flora
177(1)
Normal Flora of the Skin
177(1)
Normal Flora of the Mouth & Upper Respiratory Tract
178(1)
Normal Flora of the Intestinal Tract
179(1)
Normal Flora of the Urethra
180(1)
Normal Flora of the Vagina
180(1)
Normal Flora of the Eye (Conjunctiva)
180(2)
12. Spore-Forming Gram-Positive Bacilli: Bacillus & Clostridium Species
182(8)
Bacillus Species
182(2)
Clostridium Species
184(6)
13. Non-Spore-Forming Gram-Positive Bacilli: Corynebacterium, Propionibacterium, Listeria, Erysipelothrix & Related Pathogens
190(7)
Corynebacterium diphtheriae
190(4)
Other Coryneform Bacteria
194(1)
Listeria Monocytogenes
194(1)
Erysipelothrix rhusiopathiae
195(1)
Rothia
196(1)
14. The Staphylococci
197(6)
15. The Streptococci
203(15)
Streptococcus pneumoniae (Pneumococcus)
211(2)
Enterococci
213(3)
Other Catalase-Negative Gram-Positive Cocci
216(2)
16. Enteric Gram-Negative Rods (Enterobacteriaceae)
218(13)
Diseases Caused by Enterobacteriaceae Other Than Salmonella & Shigella
221(3)
The Shigellae
224(2)
The Salmonella-Arizona Group
226(5)
17. Pseudomonads, Acinetobacters, & Uncommon Gram-Negative Bacteria
231(6)
The Pseudomonad Group
231(3)
Acinetobacter
234(1)
Uncommon Gram-Negative Bacteria
234(3)
18. Vibrios, Campylobacters, Helicobacters, & Associated Bacteria
237(8)
The Vibrios
237(3)
Aeromonas
240(1)
Plesiomonas
240(1)
The Campylobacters
240(2)
The Helicobacters
242(3)
19. Haemophilus, Bordetella, & Brucella
245(8)
The Haemophilus Species
245(2)
The Bordetellae
247(2)
The Brucellae
249(4)
20. Yersinia, Francisella, & Pasteurella
253(5)
Yersinia pestis & Plague
253(1)
Yersinia enterocolitica & Yersinia pseudotuberculosis
254(1)
Francisella tularensis & Tularemia
255(1)
The Pasteurellae
256(2)
21. The Neisseriae
258(9)
Neisseria gonorrhoeae (Gonococcus)
258(6)
Neisseria meningitidis (Meningococcus)
264(1)
Other Neisseriae
265(2)
22. Infections Caused by Anaerobic Bacteria
267(6)
Physiology & Growth Conditions for Anaerobes
267(1)
Anaerobic Bacteria Found in Human Infections
268(2)
Pathogenesis of Anaerobic Infections
270(1)
Immunity in Anaerobic Infections
271(1)
The Polymicrobial Nature of Anaerobic Infections
271(1)
Diagnosis of Anaerobic Infections
271(1)
Treatment of Anaerobic Infections
271(2)
23. Legionellae & Unusual Bacterial Pathogens
273(6)
Legionella pneumophila & Other Legionellae
273(2)
Bacteria That Cause Vaginosis
275(1)
Streptobacillus moniliformis
275(1)
Bartonella
275(2)
Calymmatobacterium (Donovania) granulomatis
277(1)
Whipple's Disease
277(2)
24. Mycobacteria
279(10)
Mycobacterium tuberculosis
279(7)
Other Mycobacteria
286(1)
Mycobacterium leprae
287(2)
25. Spirochetes & Other Spiral Microorganisms
289(10)
Treponema
289(4)
Borrelia
293(2)
Leptospirae
295(2)
Other Spirochetal Diseases
297(2)
26. Mycoplasmas (Mollicutes) & Cell Wall-Defective Bacteria
299(5)
Mycoplasmas (Mollicutes)
299(3)
Cell Wall-Defective Bacteria
302(2)
27. Rickettsial Diseases
304(6)
28. Chlamydiae
310(9)
Chlamydia trachomatis: Ocular, Genital, & Respiratory Infections
312(4)
Chlamydia pneumoniae & Respiratory Infections
316(1)
Chlamydia psittaci & Psittacosis (Ornithosis)
316(3)
IV. VIROLOGY319(264)
29. General Properties of Viruses
319(26)
Introduction to Viruses
319(1)
Terms & Definitions in Virology
319(1)
Evolutionary Origin of Viruses
319(1)
Classification of Viruses
320(4)
Principles of Virus Structure
324(4)
Chemical Composition of Viruses
328(2)
Cultivation & Assay of Viruses
330(3)
Purification & Identification of Viruses
333(1)
Laboratory Safety
334(1)
Reaction to Physical & Chemical Agents
334(1)
Replication of Viruses: An Overview
335(4)
Genetics of Animal Viruses
339(4)
Natural History (Ecology) & Modes of Transmission of Viruses
343(1)
Diagnosis of Viral Infections
344(1)
30. Pathogenesis & Control of Viral Diseases
345(23)
Principles of Viral Diseases
345(1)
Pathogenesis of Viral Diseases
345(10)
Prevention & Treatment of Viral Infections
355(13)
31. Parvoviruses
368(6)
Properties of Parvoviruses
368(1)
Parvovirus Infections in Humans
369(3)
Animal Model of Immune Complex Disease
372(2)
32. Adenoviruses
374(11)
Properties of Adenoviruses
374(6)
Adenovirus Infections in Humans
380(5)
33. Herpesviruses
385(27)
Properties of Herpesviruses
385(6)
Herpesvirus Infections in Humans
391(21)
Herpes Simplex Viruses
391(5)
Varicella-Zoster Virus
396(5)
Cytomegalovirus
401(4)
Epstein-Barr Virus
405(4)
Human Herpesvirus 6
409(1)
Human Herpesvirus 7
409(1)
Human Herpesvirus 8
409(1)
B Virus
409(3)
34. Poxviruses
412(13)
Properties of Poxviruses
412(4)
Poxvirus Infections in Humans: Vaccinia & Variola
416(4)
Monkeypox Infections
420(1)
Cowpox Infections
420(2)
BuffalopoxInfections
422(1)
Orf Virus Infections
422(1)
Molluscum Contagiosum
422(1)
Tanapox & Yaba Monkey Tumor Poxvirus Infections
423(2)
35. Hepatitis Viruses
425(19)
Properties of Hepatitis Viruses
425(3)
Hepatitis Virus Infections in Humans
428(16)
36. Picornaviruses (Enterovirus & Rhinovirus Groups)
444(16)
Properties of Picornaviruses
444(3)
Enterovirus Group
447(9)
Poliomyelitis
447(4)
Coxackieviruses
451(3)
Echoviruses
454(1)
Other Enterovirus Types
455(1)
Enteroviruses in the Environment
456(1)
Rhinovirus Group
456(2)
Foot-and-Mouth Disease (Apthovirus of Cattle)
458(2)
37. Reoviruses & Rotaviruses
460(9)
Properties of Reoviruses
460(1)
Rotaviruses
461(3)
Reoviruses
464(1)
Orbiviruses
465(2)
Other Agents of Viral Gastroenteritis
467(2)
38. Arthropod-Borne & Rodent-Borne Viral Diseases
469(24)
Human Arbovirus Infections
472(15)
Rodent-Borne Hemorrhagic Fevers
487(6)
39. Orthomyxoviruses (Influenza Viruses)
493(14)
Properties of Orthomyxoviruses
493(6)
Influenza Virus Infections in Humans
499(8)
40. Paramyxoviruses & Rubella Virus
507(21)
Properties of Paramyxoviruses
507(5)
Parainfluenza Virus Infections
512(3)
Respiratory Syncytial Virus Infections
515(2)
Mumps Virus Infections
517(2)
Measles (Rubeola) Virus Infections
519(4)
Guillain-Barre Syndrome
523(1)
Rubella (German Measles) Virus Infections
523(5)
41. Coronaviruses
528(4)
Properties of Coronaviruses
528(2)
Coronavirus Infections in Humans
530(2)
42. Rabies & Slow Virus Infections
532(11)
Rabies
532(6)
Aseptic Meningitis
538(1)
Borna Disease
539(1)
Slow Virus Infections & Unconventional Agents
539(4)
43. Tumor Viruses & Oncogenes
543(23)
General Features of Viral Carcinogenesis
543(4)
RNA Tumor Viruses (Retroviruses)
547(7)
Cellular Oncogenes
554(3)
Tumor Suppressor Genes
557(1)
DNA Tumor Viruses
557(7)
Viruses & Human Cancer
564(2)
44. AIDS & Lentiviruses
566(17)
Properties of Lentiviruses
566(5)
HIV Infections in Humans
571(12)
V. MYCOLOGY583(34)
45. Medical Mycology (Thomas G. Mitchell, PhD)
583(34)
General Properties & Classification of Fungi
584(3)
Growth & Isolation of Fungi
587(1)
Superficial Mycoses
587(1)
Cutaneous Mycoses
588(3)
Subcutaneous Mycoses
591(4)
Systemic Mycoses (Dimorphic, Endemic Mycoses)
595(8)
Opportunistic Mycoses
603(6)
Actinomycetes
609(2)
Hypersensitivity to Fungi
611(1)
Mycotoxins
611(1)
Antifungal Chemotherapy
611(6)
VI. PARASITOLOGY617(35)
46. Medical Parasitology (Donald Heyneman, PhD)
617(35)
Classification of Parasites
617(1)
Intestinal Flagellates
618(2)
The Hemoflagellates
620(6)
Intestinal Amebas
626(4)
Balantidium coli
630(1)
Free-Living Amebas
631(1)
Blood Sporozoans
631(5)
Other Sporozoans
636(4)
Microsporida
640(1)
Helminths
640(12)
VII. DIAGNOSTIC MEDICAL MICROBIOLOGY & CLINICAL CORRELATIONS652(61)
47. Principles of Diagnostic Medical Microbiology
652(28)
Communication Between Physician & Laboratory
652(1)
Diagnosis of Bacterial & Fungal Infections
652(9)
The Importance of Normal Bacterial & Fungal Flora
661(1)
Laboratory Aids in the Selection of Antimicrobial Therapy
662(1)
Diagnosis of Infection by Anatomic Site
663(6)
Anaerobic Infections
669(1)
Diagnosis of Chlamydial Infections
669(2)
Diagnosis of Viral Infections
671(9)
48. Cases & Clinical Correlations
680(33)
Central Nervous System
680(3)
Chest
683(5)
Heart
688(1)
Abdomen
689(5)
Urinary Tract
694(1)
Bone & Soft Tissue
695(2)
Sexually Transmitted Diseases
697(3)
Mycobacterium tuberculosis Infections
700(2)
HIV-1 & AIDS
702(6)
Infections in Transplant Patients
708(5)
Index713

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