The contributions in this volume, presented at the 5th International Hydrocephalus Workshop in May 2010 in Crete, Greece, give the present state-of-the-art in timely diagnosis and treatment of hydrocephalus.The topics covered include advances in management of both pediatric and adult hydrocephalus, identifying shunt responders, clinical experiences in endoscopic third ventriculostomy, clinical trials, pathophysiology, experimental studies, and  the new classification for hydrocephalus.