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Human Population Genetics

by: Relethford, John H.

Human Population Genetics

by: Relethford, John H.

ISBN 13:
9780470464670
ISBN 10:
0470464674
Edition: 1st
Format: Paperback
Copyright: 03/27/2012
Publisher: Wiley-Blackwell

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Summary

Human Population Genetics will provide an introduction to mathematical population genetics, along with relevant examples from human (and some non-human primate) populations, and will also present concepts and methods of population genetics that are specific to the study of human populations. The purpose of this book is to provide a basic background text for advanced undergraduate and graduate students interesting in the mechanisms of human microevolution.

Foreword	p. vii
Preface	p. ix
Genetic, Mathematical, and Anthropological Background	p. 1
The Scope of Population Genetics	p. 2
Genetics Background	p. 5
Principles of Probability	p. 14
The Anthropological Connection	p. 17
A Closing Thought	p. 21
Hardy-Weinberg Equilibrium	p. 23
Genotype and Allele Frequencies	p. 24
What is Hardy-Weinberg Equilibrium?	p. 30
The Mathematics of Hardy-Weinberg Equilibrium	p. 31
Using Hardy-Weinberg Equilibrium	p. 37
Extensions of Hardy-Weinberg Equilibrium	p. 40
Hardy-Weinberg Equilibrium and Evolution	p. 44
Summary	p. 45
Inbreeding	p. 49
Quantifying Inbreeding	p. 51
Population Genetics and Inbreeding	p. 62
Inbreeding in Human Populations	p. 65
Summary	p. 75
Mutation	p. 77
The Nature of Mutations	p. 77
Models of Mutation	p. 81
Mutational History and Anthropological Questions	p. 88
Summary	p. 96
Genetic Drift	p. 101
What is Genetic Drift?	p. 102
Genetic Drift and Population Size	p. 112
Effects on Genetic Variation	p. 120
Mutation and Genetic Drift	p. 121
Coalescent Theory	p. 125
Summary	p. 131
Models of Natural Selection	p. 139
How Does Natural Selection Work?	p. 140
A General Model of Natural Selection	p. 145
Types of Natural Selection	p. 147
Other Aspects of Selection	p. 160
Summary	p. 167
Natural Selection in Human Populations	p. 181
Case Studies of Natural Selection in Human Populations	p. 182
Are Humans Still Evolving?	p. 198
Summary	p. 203
Gene Flow	p. 205
The Evolutionary Impact of Gene Flow	p. 206
Models of Gene Flow	p. 208
Gene Flow and Genetic Drift	p. 213
Estimating Admixture in Human Populations	p. 226
Summary	p. 230
Human Population Structure and History	p. 237
Case Studies of Human Population Structure	p. 238
The Origin of Modern Humans	p. 242
Case Studies of Population Origins	p. 247
Summary	p. 255
Glossary	p. 257
References	p. 267
Index	p. 279
Table of Contents provided by Ingram. All Rights Reserved.

Amazon no longer offers textbook rentals. We do!

Human Population Genetics

Human Population Genetics

9780470464670

0470464674

Summary

Author Biography

Table of Contents

Supplemental Materials

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