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Histology: A Text and Atlas; With Cell and Molecular Biology

ISBN: 9780683302424 | 0683302426
Edition: 4th
Format: Trade Paper
Publisher: Lippincott Williams & Wilkins
Pub. Date: 11/20/2002

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SummaryTable of Contents
This updated Fourth Edition best-selling text and atlas is refined in several ways. Many chapters are completely revised, and nearly half of the photographs are new. There are approximately 189 atlas plates, and over 70 new illustrations. Textboxes read as "Clinical Correlation" or "Functional Correlation", and in the text, emphasis is placed on functional integration with increased coverage of cell and molecular biology. The sentence heading and four-color art have been retained from the previous edition.
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Prefacevii
Acknowledgmentsix
Methods
2(16)
Overview of Methods Used in Histology
2(1)
Tissue Preparation
3(2)
Histochemistry and Cytochemistry
5(6)
Functional Considerations: Feulgen Microspectrophotometry
8(3)
Microscopy
11(7)
Functional Considerations: Development of Electron Microscopy
14(1)
Functional Considerations: Special Staining for Transmission Electron Microscopy
15(1)
Proper Use of the Light Microscope
16(2)
The Cell
18(60)
Overview of Cell Structure
19(1)
Cytoplasm
19(26)
Membranous Organelles
45(1)
Nonmembranous Organelles
45(15)
Clinical Correlations: Abnormalities in Microtubules and Filaments
55(5)
Nucleus
60(8)
Cell Renewal
68(1)
Cell Cycle
68(4)
Cell Death
72(6)
Tissues: Concept and Classification
78(8)
Overview of Tissues
78(1)
Epithelium
79(1)
Connective Tissue
80(1)
Muscle Tissue
80(1)
Nerve Tissue
81(3)
Clinical Correlations: Ovarian Teratomas
82(2)
Identifying Tissues
84(2)
Epithelial Tissue
86(40)
Overview of Epithelial Structure and Function
87(1)
Classification of Epithelium
88(2)
Cell Polarity
90(1)
The Apical Domain and Its Modifications
90(6)
Clinical Correlations: Immotile Cilia Syndrome
95(1)
The Lateral Domain and Its Specializations in Cell-to-Cell Adhesion
96(8)
The Basal Domain and Its Specializations in Cell-to-Extracellular Matrix Adhesion
104(7)
Functional Considerations: Basement Membrane and Basal Lamina Terminology
107(4)
Glands
111(3)
Histogenesis of Epithelium
114(2)
Epithelial Cell Renewal
116(10)
Functional Considerations: Mucous and Serous Membranes
117(3)
Atlas Plates
Simple Squamous and Cuboidal Epithelia
120(2)
Simple and Stratified Epithelia
122(2)
Stratified Epithelia and Epithelioid Tissues
124(2)
Connective Tissue
126(30)
General Structure and Function of Connective Tissue
126(2)
Embryonic Connective Tissue
128(1)
Connective Tissue Proper
128(3)
Connective Tissue Fibers
131(8)
Clinical Correlations: Collagenopathies
136(3)
Ground Substance
139(1)
Extracellular Matrix
139(2)
Connective Tissue Cells
141(3)
Functional Considerations: The Mononuclear Phagocytotic System
144(12)
Atlas Plates
Loose and Dense Connective Tissue
150(2)
Dense Regular Connective Tissue, Tendons, and Ligaments
152(2)
Elastic Fibers and Elastic Lamellae
154(2)
Adipose Tissue
156(8)
Overview of Adipose Tissue
156(1)
White Adipose Tissue
156(4)
Brown Adipose Tissue
160(4)
Clinical Correlations: Adipose Tissue Tumors
162(2)
Cartilage
164(16)
Overview of Cartilage
164(1)
Hyaline Cartilage
164(5)
Elastic Cartilage
169(1)
Fibrocartilage
169(1)
Histogenesis, Growth, and Repair of Hyaline Cartilage
170(10)
Atlas Plates
Hyaline Cartilage
172(2)
Cartilage and the Developing Skeleton
174(2)
Elastic Cartilage
176(2)
Fibrocartilage
178(2)
Bone
180(34)
Overview of Bone
180(1)
Bones and Bone Tissue
181(1)
General Structure of Bones
182(4)
Clinical Correlations: Articular Catilage and Joint Diseases
183(3)
Cells of Bone Tissue
186(7)
Bone Formation
193(7)
Clinical Correlations: Nutritional Factors in Bone Formation
199(1)
Biologic Mineralization and Matrix Vesicles
200(1)
Physiologic Aspects of Bone
201(1)
Functional Considerations: Hormonal Regulation of Bone Growth
201(1)
Fractures and Bone Repair
201(13)
Atlas Plates
Bone, Ground Section
204(2)
Spongy and Compact Bone
206(2)
Endochondral Bone Formation I
208(2)
Endochondral Bone Formation II
210(2)
Intramembranous Bone Formation
212(2)
Blood
214(32)
Overview of Blood
214(1)
Plasma
215(2)
Erythrocytes
217(4)
Clinical Correlations: ABO and Rh Blood Group Systems
219(1)
Clinical Correlations: Hemoglobin Disorders
220(1)
Leukocytes
221(8)
Platelets
229(2)
Formation of Blood Cells (Hemopoiesis)
231(9)
Clinical Correlations: Hemoglobin Breakdown and Jaundice
237(3)
Bone Marrow
240(6)
Atlas Plates
Erythrocytes and Agranulocytes
242(2)
Granulocytes
244(2)
Muscle Tissue
246(36)
Overview and Classification of Muscle
246(2)
Skeletal Muscle
248(14)
Functional Considerations: Muscle Metabolism and Ischemia
250(4)
Clinical Correlations: Muscular Dystrophy-Dystrophin and Dystrophin-Associated Proteins
254(2)
Functional Considertions: The Sliding Filament Model
256(3)
Clinical Correlations: Myasthenia Gravis
259(3)
Cardiac Muscle
262(3)
Smooth Muscle
265(17)
Functional Considerations: Complexity of Smooth Muscle Innervation
269(1)
Functional Considerations: Comparison of the Three Muscle Types
270(2)
Atlas Plates
Skeletal Muscle
272(2)
Musculotendinous Jucntion and Neuromuscular Junction
274(2)
Cardiac Muscle
276(2)
Cardiac Muscle, Purkinje Fibers
278(2)
Smooth Muscle
280(2)
Nerve Tissue
282(44)
Overview of the Nervous System
283(1)
Composition of Nerve Tissue
283(1)
The Neuron
284(9)
Clinical Correlations: Parkinson's Disease
292(1)
Supporting Cells of the Nervous System
293(10)
Clinical Correlations: Demyelinating Diseases
297(6)
Origin of Nerve Tissue Cells
303(1)
Organization of the Peripheral Nervous System
303(8)
Organization of the Central Nervous System
311(2)
Response of Neurons to Injury
313(13)
Sympathetic and Dorsal Root Ganglia
316(2)
Peripheral Nerve
318(2)
Cerebrum
320(2)
Cerebellum
322(2)
Spinal Cord
324(2)
Cardiovascular System
326(30)
Overview of the Cardiovascular System
326(1)
General Features of Arteries and Veins
327(1)
Arteries
328(10)
Clinical Correlations: Hypertension
336(1)
Clinical Correlations: Atherosclerosis
337(1)
Capillaries
338(2)
Arteriovenous Shunts
340(1)
Veins
341(2)
Heart
343(4)
Clinical Correlations: Ischemic Heart Disease
346(1)
Lymphatic Vessels
347(9)
Atlas Plates
Heart
348(2)
Aorta
350(2)
Muscular Arteries and Veins
352(2)
Arterioles and Lymphatic Vessels
354(2)
Lymphatic System
356(44)
Overview of the Lymphatic System
356(1)
Lymphatic Cells
357(11)
Functional Considerations: Origin of the Names T Lymphocyte and B Lymphocyte
361(4)
Clinical Correlations: Hypersensitivity Reactions
365(2)
Clinical Correlations: Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS)
367(1)
Lymphatic Tissues and Organs
368(32)
Atlas Plates
Tonsil
388(2)
Lymph Node I
390(2)
Lymph Node II
392(2)
Spleen I
394(2)
Spleen II
396(2)
Thymus
398(2)
Integumentary System
400(34)
Overview of the Integumentary System
400(1)
Layers of the Skin
401(4)
Cells of the Epidermis
405(6)
Functional Considerations: Skin Color
409(2)
Structures of the Skin
411(23)
Functional Considerations: Hair Growth and Hair Characteristics
415(1)
Functional Considerations: The Role of Sebum
415(4)
Clinical Correlations: Sweating and Disease
419(2)
Clinical Correlations: Skin Repair
421(1)
Atlas Plates
Skin I
422(2)
Skin II
424(2)
Eccrine and Apocrine Sweat Glands
426(2)
Sweat and Sebaceous Glands
428(2)
Integument and Sensory Organs
430(2)
Hair Follicle and Nail
432(2)
Digestive System I: Oral Cavity and Associated Structures
434(40)
Overview of the Digestive System
434(1)
Oral Cavity
435(2)
Tongue
437(3)
Clinical Correlations: Inherited Absence of Taste
440(1)
Teeth and Supporting Tissues
440(14)
Clinical Correlations: Classification of Permanent (Secondary) and Deciduous (Primary) Dentition
441(8)
Functional Considerations: Histologic Preparation of Tooth Tissues
449(4)
Clinical Correlations: Dental Caries
453(1)
Salivary Glands
454(20)
Atlas Plates
Lip, A Mucocutaneous Junction
462(2)
Tongue I
464(2)
Tongue II
466(2)
Submandibular Gland
468(2)
Parotid Gland
470(2)
Sublingual Gland
472(2)
Digestive System II: Esophagus and Gastrointestinal Tract
474(58)
Overview of the Esophagus and Gastrointestinal Tract
475(3)
Esophagus
478(2)
Stomach
480(11)
Clinical Correlations: Pernicious Anemia and Peptic Ulcer Disease
487(2)
Functional Considerations: Enteroendocrine Cells, APUD Cells and Gastrointestinal Hormones
489(1)
Clinical Correlations: Zollinger-Ellison Syndrome
490(1)
Small Intestine
491(10)
Large Intestine
501(31)
Functional Considerations: Digestive and Absorptive Functions of Enterocytes
502(7)
Functional Considerations: Immune Functions of the Alimentary Canal
509(1)
Atlas Plates
Esophagus
510(2)
Esophagus and Stomach, Cardiac Region
512(2)
Stomach I
514(2)
Stomach II
516(2)
Gastroduodenal Junction
518(2)
Duodenum
520(2)
Jejunum
522(2)
Ileum
524(2)
Colon
526(2)
Appendix
528(2)
Anorectal Junction
530(2)
Digestive System III: Liver, Gallbladder, and Pancreas
532(36)
Liver
532(16)
Clinical Correlations: Congestive Heart Failure and Liver Necrosis
539(7)
Clinical Correlations: Lipoproteins
546(2)
Gallbladder
548(3)
Pancreas
551(17)
Functional Considerations: Insulin Synthesis, An Example of Posttranslational Processing
559(1)
Atlas Plates
Liver I
560(2)
Liver II
562(2)
Gallbladder
564(2)
Pancreas
566(2)
Respiratory System
568(34)
Overview of the Respiratory System
568(1)
Nasal Cavities
569(4)
Pharynx
573(1)
Larynx
573(2)
Clinical Correlations: Metaplasia
575(1)
Trachea
575(4)
Bronchi
579(1)
Bronchioles
580(3)
Clinical Correlations: Cystic Fibrosis
582(1)
Alveoli
583(7)
Clinical Correlations: Emphysema and Pneumonia
588(2)
Blood Supply
590(1)
Lymphatic Vessels
590(1)
Nerves
590(12)
Atlas Plates
Olfactory Mucosa
592(2)
Larynx
594(2)
Trachea
596(2)
Bronchiole and End Respiratory Passages
598(2)
Wall of Terminal Bronchiole, Respiratory Bronchiole, and Alveolus
600(2)
Urinary System
602(40)
Overview of the Urinary System
603(1)
Functional Considerations: Vitamin D
603(1)
General Structure of the Kidney
604(12)
Clinical Considerations: Urinalysis
614(2)
Clinical Correlations: Renin-Angiotensin-Aldosterone System and Hypertension
616(1)
Kidney Tubule Function
616(6)
Functional Considerations: Structure and Function of Aquaporin Water Channels
619(3)
Interstitial Cells
622(1)
Functional Considerations: Hormonal Regulation of Collecting Duct Function
622(1)
Histophysiology of the Kidney
623(1)
Blood Supply
624(1)
Lymphatic Vessels
625(1)
Nerve Supply
626(1)
Ureter, Urinary Bladder, and Urethra
626(16)
Atlas Plates
Kidney I
630(2)
Kidney II
632(2)
Kidney III
634(2)
Kidney IV
636(2)
Ureter
638(2)
Urinary Bladder
640(2)
Endocrine Organs
642(40)
Overview of the Endocrine System
642(2)
Pituitary Gland (Hypophysis)
644(9)
Functional Considerations: Pituitary Secretion and Hypothalamic Regulating Hormones
650(3)
Pineal Gland
653(2)
Thyroid Gland
655(4)
Functional Considerations: Feedback Control of Thyroid Hormone Synthesis
659(1)
Clinical Correlations: Abnormal Thyroid Function
659(1)
Parathyroid Glands
659(2)
Adrenal Glands
661(21)
Functional Considerations: Chromaffin Cells
665(3)
Functional Considerations: Cholesterol
668(2)
Atlas Plates
Pituitary I
670(2)
Pituitary II
672(2)
Pineal Gland
674(2)
Parathyroid and Thyroid Glands
676(2)
Adrenal Gland I
678(2)
Adrenal Gland II
680(2)
Male Reproductive System
682(44)
Overview of the Male Reproductive System
683(1)
Testis
683(7)
Spermatogenesis
690(6)
Functional Considerations: Hormonal Regulation of Spermatogenesis
690(4)
Clinical Correlations: Factors Affecting Spermatogenesis
694(2)
Seminiferous Tubules
696(5)
Clinical Correlations: Sperm-Specific Antigens and the Immune Response
700(1)
Intratesticular Ducts
701(1)
Excurrent Duct System
702(4)
Accessory Sex Glands
706(4)
Clinical Correlations: Benign Prostatic Hypertrophy and Prostatic Cancer
709(1)
Semen
710(1)
Penis
710(16)
Clinical Correlations: Mechanism of Erection and Erectile Dysfunction
712(2)
Atlas Plates
Testis I
714(2)
Testis II
716(2)
Ductuli Efferentes and Epididymis
718(2)
Spermatic Cord and Ductus Deferens
720(2)
Prostate Gland
722(2)
Seminal Vesicle
724(2)
Female Reproductive System
726(62)
Overview of the Female Reproductive System
727(1)
Ovary
728(14)
Clinical Correlations: Polycystic Ovarian Disease
735(4)
Clinical Correlations: In Vitro Fertilization
739(2)
Functional Considerations: Summary of Hormonal Regulation of the Ovarian Cycle
741(1)
Uterine Tubes
742(1)
Uterus
743(8)
Placenta
751(4)
Clinical Correlations: Fate of Mature Placenta at Birth
755(1)
Vagina
755(2)
Clinical Corelations: Cytologic Pap Smears
757(1)
External Genitalia
757(1)
Mammary Glands
758(30)
Functional Considerations: Lactation and Infertility
763(1)
Atlas Plates
Ovary I
764(2)
Ovary II
766(2)
Corpus Luteum
768(2)
Oviduct-Uterine Tube
770(2)
Uterus I
772(2)
Uterus II
774(2)
Cervix
776(2)
Placenta I
778(2)
Placenta II
780(2)
Vagina
782(2)
Mammary Gland
784(2)
Mammary Gland, Late Proliferative and Lactating
786(2)
Eye
788(32)
Overview of the Eye
788(1)
General Structure of the Eye
788(4)
Microscopic Structure of the Eye
792(28)
Clinical Correlations: Glaucoma
799(2)
Clinical Correlations: Retinal Detachment
801(5)
Clinical Correlations: Age-Related Macular Degeneration (ARMD)
806(6)
Atlas Plates
Eye I
812(2)
Eye II: Retina
814(2)
Eye III: Anterior Segment
816(2)
Eye IV: Sclera, Cornea, and Lens
818(2)
Ear
820(23)
Overview of the Ear
820(1)
External Ear
821(1)
Middle Ear
821(3)
Internal Ear
824(19)
Clinical Correlatons: Vertigo
829(3)
Clinical Correlations: Hearing Loss-Vestibular Dysfunction
832(6)
Atlas Plates
Ear
838(2)
Organ of Corti
840(3)
Index843

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