9783527320288

Summarizing molecular aspects, diagnostic as well as therapeutic issues, this book is the very first and most comprehensive on hereditary aspects of tumor diseases. All the contributors have been made fellows of the Ingrid zu Solms Foundation due to their outstanding achievements in scientific research, and they discuss here the latest aspects in the diagnosis, disease management, and treatment of hereditary tumor diseases and syndromes. A must-have ready reference for medical and biology students, MDs, PhDs, physicians, and researchers.

Heike Allgayer is the Department Head of Experimental Surgery at the Mannheim Medical Faculty of University of Heidelberg, and also Head of the Molecular Oncology of Solid Tumor's Unit at German Cancer Research Center (DKFZ), Heidelberg. Her major research interests include tumor progression, invasion and metastasis, molecular determinants of carcinogenesis and cancer progression, translational research, and molecular staging of cancer. She has authored 145 scientific publications and has received 19 scientific awards.

Helga Rehder, MD, PhD, former head of the Institute of Clinical Genetics of the Philipps-University Marburg, is now Guest Professor of the Department of Medical Genetics at University Vienna. As a Pathologist and Human Geneticist, her fields of research activities were 'Fetal Pathology and Syndromology' and 'Tumor Genetics'. Her publication list covers 138 papers and she has received four awards, including the Hans Nachtsheim-Award of the Society of Human Genetics and the Jacob Henle-Medal' of the University G+¦ttingen. Helga Rehder is member of the Curatory of the Ingrid-zu-Solms-Foundation, and head of the Consultive Committee for the Ingrid zu Solms-Award for Woman-Scientists.

Simone Fulda is Full Professor of Pediatric Research and Head of the Clinical Research Group on Apoptosis at Ulm University, Germany. She trained as pediatric oncologist and molecular/cell biologist in Germany, Harvard Medical School Boston, San Francisco, Phoenix and in the UK. Her research focusses on elucidating apoptosis signaling pathways in cancer and during cancer therapy. She holds several international patent applications and has received various scientific awards, including the Schweizgurth Prize of the International Society of Pediatric Oncology, the Kind-Philipp-Prize of the German Society of Pediatric Oncology & Hematology, the Vincenz-Czerny Preis of the German Society of Hematology & Oncology, the Research Award of the Ingrid zu Solms-Foundation, Merckle Research Award, Johann-Georg-Zimmermann Award and the Heisenberg excellence grant of the German Science Foundation. She is member of several international advisory boards, editorial board member of Cancer Research and Recent Patents on Anti-Cancer Drug Discovery and Editor of "Apoptosis and Cancer Therapy" published by Wiley-VCH.

Hereditary Tumors-General Aspects
Tumor Invasion, Progression and Metastasis
The Genetic Background of Hereditary Tumor Diseases
Syndromal Types Of Hereditary Tumors
Family Cancer Syndromes
Genetic Dysmorphic Syndromes Leading to Tumorigenesis
Site-Specific Hereditary Tumors
Hereditary Brain Tumors
Neurofibromatosis
Retinoblastoma: The Prototypic Hereditary Tumor (
Hereditary Cancer in the Head and Neck
Hereditary Medullary and Familial Nonmedullary Thyroid Carcinoma
Lung Tumors (Danson, Teare, Woll) Hereditary Breast Cancer
The Hereditary Ovarian and Endometrial Cancer
Prostate Cancer
Wilms and Rhabdoid Tumors of the Kidney
Hereditary Renal Tumours of the Adult
Gastrointestinal Polyposis Syndromes
Lynch Syndrome (HNPCC)
Gastrointestinal Stromal Tumors (GISTs)
Hereditary Gastric Cancer
Pancreatic Cancer
Liver Tumors
DNA-Repair Deficiency and Cancer
Lessons from Lymphoma
Leukemia (Fonatsch) Malignant MelanomaBerking, Bosserhoff
Xeroderma Pigmentosum, Cockayne Syndrome, Trichothiodystrophy - Defects in DNA Repair and Carcinogenesis
Hereditary Tumors in Children
Sarcomas and Bone Tumors in Adulthood
Genetic Counselling; Psychooncology; And General Perspectives For Therapeutic Strategies
Genetic Counselling for Hereditary Tumors
Psychooncologic Aspects of Hereditary Tumors and Predictive Testing
Molecular Targeted Therapy
Table of Contents provided by Publisher. All Rights Reserved.

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Hereditary Tumors : From Genes to Clinical Consequences

Hereditary Tumors : From Genes to Clinical Consequences

3527320288

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