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Handbook of Iron Overload Disorders

ISBN: 9780521873437 | 0521873436
Edition: 1st
Format: Hardcover
Publisher: Cambridge University Press
Pub. Date: 9/6/2010

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SummaryTable of Contents
The Handbook of Iron Overload Disorders is a compact guide to normal iron metabolism, iron-related pathobiology, and the diagnosis and management of heritable and acquired iron overload disorders. Essential reading for practising medical specialists in the fields of hematology, gastroenterology, hepatology, rheumatology, endocrinology, diabetology, neurology, oncology, dermatology and internal medicine.

A practical, clinically-oriented handbook of iron overload disorders giving a compact guide to normal iron metabo... MORE
Foreword
Preface
History of iron overload disorders
Normal iron absorption and metabolism
Iron toxicity
Tests for hemochromatosis and iron overload
Complications of hemochromatosis and iron overload
Insulin resistance and iron overload
Infections and immunity
Classical and atypical hfe hemochromatosi... MORE
Heterozygosity for hfe c282y
Porphyria cutanea tarda
Mitochondrial mutations as modifiers of hemochromatosis
Hemochromatosis associated with ferroportin gene (slc40a1) mutations
Hemochromatosis associated with hemojuvelin gene (hjv) mutations
Hemochromatosis associated with hepcidin gene (hamp) mutations
Hemochromatosis associated with transferrin receptor-2 gene (tfr2) mutations
Iron overload associated with ire mutation of ferritin heavy-chain gene (fth1)
Hereditary hyperferritinemia-cataract syndrome: ire mutations of ferritin light chain gene (ftl)
Iron overload in native Africans and African Americans
Hereditary atransferrinemia
Divalent metal transporter-1 (dmt1) iron overload
Iron overload associated with thalassemia syndromes
Iron overload associated with hemoglobinopathies
Iron overload associated with pyruvate kinase deficiency
Iron overload associated with congenital dyserythropoietic anemias
Hereditary sideroblastic anemias
Pearson marrow-pancreas syndrome
Acquired sideroblastic anemias
Hereditary aceruloplasminemia
Friedreich ataxia and cardiomyopathy
Pantothenate kinase (pank2)-associated neurodegeneration
Neuroferritinopathies
Gracile syndrome
Neonatal hemochromatosis
Iron overload due to excessive supplementation
Localized iron overload
Management of iron overload
Population screening for hemochromatosis
Ethical, legal, and social issues
Directions for future research
Index
Table of Contents provided by Publisher. All Rights Reserved.


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