Locke Karriker, DVM, MS, DACVPM, is Associate Professor of Veterinary Diagnostic and Production Animal Medicine and Director of the Swine Medicine Education Center at Iowa State University in Ames, Iowa.

Alejandro Ramirez, DVM, MPH, PhD, DACVPM, is Assistant Professor of Veterinary Diagnostic and Production Animal Medicine at Iowa State University in Ames, Iowa.

Kent J. Schwartz, DVM, MS, is Veterinary Diagnostician at the Iowa State University Veterinary Diagnostic Laboratory in Ames, Iowa.

Gregory W Stevenson, DVM, PhD, DACVP, is Professor of Veterinary Pathology and Senior Diagnostic Veterinary Pathologist at Iowa State University in Ames, Iowa.

Contributing Authors xiii

Editors' Note xxiii

SECTION I VETERINARY PRACTICE

1 Herd Evaluation 5

2 Differential Diagnosis of Diseases 18

3 Behavior and Welfare 32

4 Longevity in Breeding Animals 50

5 Effect of the Environment on Health 60

6 Optimizing Diagnostic Value and Sample Collection 67

7 Diagnostic Tests, Test Performance, and Considerations for Interpretation 77

8 Analysis and Use of Diagnostic Data 94

9 Drug Pharmacology, Therapy, and Prophylaxis 106

10 Anesthesia and Surgical Procedures in Swine 119

11 Disease Transmission and Biosecurity 141

12 Preharvest Food Safety,

13 Special Considerations for Show and Pet Pigs 179

SECTION II BODY SYSTEMS

14 Cardiovascular and Hematopoietic Systems 189

15 Digestive System 199

16 Immune System 227

17 Integumentary System: Skin, Hoof, and Claw 251

18 Mammary System 270

19 Nervous and Locomotor Systems 294

20 Diseases of the Reproductive System 329

21 Respiratory System 348

22 Urinary System 363

SECTION III VIRAL DISEASES

23 Overview of Viruses 383

24 Porcine Adenoviruses 392

25 African Swine Fever Virus 396

26 Porcine Circoviruses 405

27 Porcine Anelloviruses 418

28 Herpesviruses 421

29 Porcine Parvovirus 447

30 Swinepox Virus 456

31 Porcine Reproductive and Respiratory Syndrome Virus (Porcine Arterivirus) 461

32 Porcine Astroviruses 487

33 Bunyaviruses 490

34 Porcine Caliciviruses 493

35 Coronaviruses 501

36 Filovirus 525

37 Flaviviruses 528

38 Pestiviruses 538

39 Hepatitis E Virus 554

40 Influenza Virus 557

41 Paramyxoviruses 572

42 Picornaviruses 587

43 Reoviruses (Rotaviruses and Reoviruses) 621

44 Retroviruses 635

45 Rhabdoviruses 639

46 Togaviruses 644

SECTION IV BACTERIAL DISEASES

47 Overview of Bacteria 649

48 Actinobacillosis 653

49 Bordetellosis 670

50 Brachyspiral Colitis 680

51 Brucellosis 697

52 Clostridiosis 709

53 Colibacillosis 723

54 Erysipelas 750

55 Glässer’s Disease 760

56 Leptospirosis 770

57 Mycoplasmosis 779

58 Pasteurellosis 798

59 Proliferative Enteropathy 811

60 Salmonellosis 821

61 Staphylococcosis 834

62 Streptococcosis 841

63 Tuberculosis 856

64 Miscellaneous Bacterial Infections 866

SECTION V PARASITIC DISEASES

65 External Parasites 885

66 Coccidia and Other Protozoa 895

67 Internal Parasites: Helminths 908

SECTION VI NONINFECTIOUS DISEASES

68 Nutrient Deficiencies and Excesses 923

69 Mycotoxins in Grains and Feeds 938

70 Toxic Minerals, Chemicals, Plants, and Gases 953

Index 968

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