Written for basic scientists, students, and educators, this first-of-its-kind reference covers immunity, immunopathology, and direct intercellular communication through gap channels. It covers immunology and cell biology, inflammation, and inflammatory diseases; including lung, brain, and skin inflammation, Athrosclerosis, and connexin-based therapeutic approaches in inflammatory diseases. Chapters cover basic research, clinical practice, and commercial applications and discuss the importance of cellular interactions, especially connectivity in the component cells of the immune system. This reference also describes connexin-specific pharmacology and therapeutic approaches under development for future use, especially in the areas of wound healing. A website is available as well, upon book purchase.