9780470587201

Presenting an overview of chiral drugs and their impact in the pharmaceutical industry, Chiral Drugs: Chemistry and Biological Action provides an integrated perspective of chiral drugs from concept, synthesis, and pharmaceutical properties. The book includes important chiral technologies and reviews of 200 chiral drugs that have either been approved or made it to advanced trials. The book's interdisciplinary approach combines synthetic organic chemistry, medicinal chemistry, and pharmacology in a way that fosters cooperation among interdisciplinary scientists and researchers in both academia and the pharma or biotech industries.

Guo-Qiang Lin, is a professor at the Shanghai Institute of Organic Chemistry and an adjunct professor at Fundan University, China. He is the Director of the Division of Chemical Science of the National Natural Science Foundation of China. Among Professor Lin's publications are the Wiley books Principles and Applications of Asymmetric Synthesis and Biocatalysis for the Pharmaceutical Industry. Qi-Dong You, PhD, is the Dean and a professor of the School of Pharmacy at China Pharmaceutical University. He is an Associate Editor of Progress in Pharmaceutical Sciences and serves on the Editorial Board of the International Journal of Medicinal Chemistry and Acta Pharmaceutica Sinica. Dr. You is a coauthor of over eighty publications, and an inventor or co-inventor of over twenty patent applications and patents. Jie-Fei Cheng, PhD, is the Director of Otsuka Shanghai Research Institute, a fully owned subsidiary of Otsuka Pharmaceutical Co., Ltd Japan. Formerly an associate professor at Shanghai Institute of Organic Chemistry, he has worked for over fifteen years in the pharmaceutical and biotech industries in the Untied States. Dr. Cheng is a coauthor of over fifty peer-reviewed publications, and an inventor or coinventor of over twenty patent applications and patents.

About the Editors	p. vii
Contributors	p. ix
Introduction	p. 1
Overview of Chirality And Chiral Drugs	p. 3
Chiral Drugs Through Asymmetric Synthesis	p. 29
Chiral Drugs Via Biocatalytical Approaches	p. 77
Resolution of Chiral Drugs	p. 137
Fluorine-Containing Chiral Drugs	p. 195
Industrial Application Of Chiral Technologies	p. 253
Structural Basis And Computational Modeling Of Chiral Drugs	p. 297
Pharmacology Of Chiral Drugs	p. 323
Pharmacokinetics Of Chiral Drugs	p. 347
Toxicology Of Chiral Drugs	p. 381
Representative Chiral Drugs	p. 401
Index	p. 449
Table of Contents provided by Ingram. All Rights Reserved.

What is included with this book?

The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.

Amazon no longer offers textbook rentals. We do!

Chiral Drugs Chemistry and Biological Action

Chiral Drugs Chemistry and Biological Action

0470587202

Summary

Author Biography

Table of Contents

Supplemental Materials

Write a Review