Carbohydrate Recognition : Biological Problems, Methods, and Applications
ISBN: 9780470592076 | 0470592079
Edition: 1stFormat: Hardcover
Publisher: Wiley
Pub. Date: 9/6/2011
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This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.
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| Preface | p. vii |
| Contributors | p. ix |
| Mammalian Glycan Biosynthesus: Building a Template for Biological recognition | p. 1 |
| The Roles of Carbohydrates Binding in cell Adhesion and Inflammation | p. 33 |
| The Role of Carbohydrates in Viral Infections | p. 65 |
| The Role of Carbohydrates in Bacterial Infections | p. 93 |
| The Roles of Carbohydrates Binding in Fertilization | p. 107 |
| C... MORE | p. 133 |
| Galectings and their Rple in Various Biological Processes | p. 157 |
| Glycoimmunology | p. 181 |
| Tools for Glycomics: Glycan and Lectin Microarrays | p. 205 |
| Combinatorial Biosynthesis of Complex Carbohyrates | p. 299 |
| Mass Spectrometery in Carbohydrate Sequencing and Binding Analysis | p. 257 |
| Synthetic Lectin Mimics Artificial Carbohydrates Receptors | p. 301 |
| Lectin Binding and its Structurial Basis | p. 329 |
| Multivalency in Carbohydrate Binding | p. 349 |
| Carbohydrate Binding Agents: Potential The rapeutics with Multiple Inhibitory Actions Against Enveloped Viruses | p. 371 |
| Informatics for Glycobiology and Glycomics | p. 409 |
| Index | p. 427 |
| Table of Contents provided by Ingram. All Rights Reserved. |
Binghe Wang, PHD, is Professor and Chair of the Department of Chemistry at Georgia State University as well as Georgia Research Alliance Eminent Scholar in Drug Discovery. He is Editor-in-Chief of the journal Medicinal Research Reviews, Series Editor for the Wiley Series in Drug Discovery and Development, and editor of Drug Delivery: Principles and Applications and Chemosensors: Principles, Strategies, and Applications (Wiley). Geert-Jan Boons, PhD, is Franklin Professor of Chemistry and Professor in the Complex Carbohydrate Research Center at the University of Georgia. He is on the editorial boards of several journals on carbohydrates, including European Journal of Chemistry and Journal of Carbohydrate Chemistry, and is also coeditor of Carbohydrate-Based Immunotherapies and Vaccines (Wiley).
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