The current science of pharmacology-and its clinical applications-at your fingertips Now in its 25th year of publication, Basic and Clinical Pharmacology is the most up-to-date and complete pharmacology textbook available. Through nine previous editions it has set the standard for concise and easy-to-read, yet comprehensive coverage of pharmacology. The text's integration of basic with clinical science makes it well suited for an integrated organ-system-based curricula as well as the more traditional curricula. Features In-depth coverage of key pharmacology topics, from basic principles to pharmacologic considerations for autonomic, cardiovascular-renal, smooth muscle, CNS, endocrine, antimicrobial, and chemotherapeutic and immunotherapeutic drugs Updated with dozens of new, recently approved drugs, including monoclonal antibodies Detailed review of the mechanism of action and toxicities of traditional and newer drugs Critical discussions of treatment strategies and recommended drugs for all major diseases Valuable section on toxicology that provides an introduction to occupational and environmental toxicology; heavy metal intoxication and chelators; and management of the poisoned patient Ready-to-use, study-enhancing features, including special interest boxes, lists of common preparations, and dosage information Unique evidence-based chapters on abused drugs; special aspects of perinatal, pediatric, and geriatric pharmacology; and over-the-counter drugs, herbal medications, and nutritional supplements More than 500 concept-clarifying illustrations and tables throughout

36. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout

VII: ENDOCRINE DRUGS

37. Hypothalamic & Pituitary Hormones

38. Thyroid & Antithyroid Drugs

39. Adrenocorticosteroids & Adrenocortical Antagonists

40. The Gonadal Hormones & Inhibitors

41. Pancreatic Hormones & Antidiabetic Drugs

42. Agents That Affect Bone Mineral Homeostasis

VIII: CHEMOTHERAPEUTIC DRUGS

43. Beta-Lactam Antibodies & Other Inhibitors of Cell Wall Synthesis

44. Chloramphenicol. Tetracyclines, Macrolides, Clindamycin, & Streptogramins

45. Aminoglycosides & Spectinomycin

46. Sulfonamides, Trimethoprim, & Quinolones

47. Antimycobacterial Drugs

48. Antifungal Drugs

49. Antiviral Agents

50. Miscellaneous Antimicrobial Drugs: Disinfectants, Antiseptics, & Sterilants

51. Clinical Use of Antimicrobial Agents

52. Basic Principles of Antiparasitic Chemotherapy

53. Antiprotozoal Drugs

54. Clinical Pharmacology of the Anthelmintic Drugs

55. Cancer Chemotherapy

56. Immunopharmacology

IX. TOXICOLOGY

57. Introduction to Toxicology: Occupational & Environmental

58. Heavy Metal Intoxication & Chelators

59. Management of the Poisoned Patient

X. SPECIAL TOPICS

60. Special Aspects of Perinatal & Pediatric Pharmacology

61. Special Aspects of Geriatric Pharmacology

62. Dermatologic Pharmacology

63. Drugs Used in Gastrointestinal Diseases

64. Therapeutic & Toxic Potential of Over-the-Counter Agents, Botanicals, and Nutritional Supplements

Appendix I. Vaccines, Immune Globulins, & Other Complex

Biologic Products

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Basic and Clinical Pharmacology

Basic and Clinical Pharmacology

9780071451536

0071451536

Summary

Table of Contents

11. Antihypertensive Agents

12. Vasodilators & the Treatment of Angina Pectoris

13. Drugs Used in Heart Failure

14. Agents Used in Cardiac Arrhythmias

15. Diuretic Agents

IV. DRUGS WITH IMPORTANT ACTIONS ON SMOOTH MUSCLE

16. Histamine, Serotonin, & the Ergot Alkaloids

17. Vasoactive Peptides

18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds

19. Nitric Oxide, Donors, & Inhibitors

20. Drugs Used in Asthma

V. DRUGS THAT ACT IN THE CENTRAL NERVOUS SYSTEM

21. Introduction to the Pharmacology of CNS Drugs

22. Sedative-Hypnotic Drugs

23. The Alcohols

24. Antiseizure Drugs

25. General Anesthetics

26. Local Anesthetics

27. Skeletal Muscle Relaxants

28. Pharmacologic Management of Parkinsonism & Other Movement Disorders

29. Antipsychotic Agents & Lithium

30. Antidepressant Agents

31. Opioid Analgesics & Antagonists

32. Drugs of Abuse

VI. DRUGS USED TO TREAT DISEASES OF THE BLOOD, INFLAMMATION, & GOUT

33. Agents Used in Anemias; Hematopoietic Growth Factors

34. Drugs Used in Disorders of Coagulation

35. Agents Used in Hyperlipidemia