FREE SHIPPING BOTH WAYS
ON EVERY ORDER!
LIST PRICE:
$99.95

OUR PRICE:
$69.27

You may extend rentals at any time.


Benign and Pathological Chromosomal Imbalances: Microscopic and Submicroscopic Copy Number Vari...

ISBN: 9780124046313 | 0124046312
Format: Hardcover
Publisher: Academic Pr
Pub. Date: 10/1/2013

Why Rent from Knetbooks?

Because Knetbooks knows college students. Our rental program is designed to save you time and money. Whether you need a textbook for a semester, quarter or even a summer session, we have an option for you. Simply select a rental period, enter your information and your book will be on its way!

Top 5 reasons to order all your textbooks from Knetbooks:

  • We have the lowest prices on thousands of popular textbooks
  • Free shipping both ways on ALL orders
  • Most orders ship within 48 hours
  • Need your book longer than expected? Extending your rental is simple
  • Our customer support team is always here to help
Given technology-driven FISH, aCGH approaches have yet to reach the much-touted promise of universal coverage or cost efficacy to sample investigated, deep chromosome analysis and molecular cytogenetics will remain relevant for technology translation, study design and therapeutic assessment for many years. This book provides a classification system to clarify the disease implications of cytogenetically visible copy number variants using cytogenetic assessment of heterochromatic or euchromatic DNA variants. While variants of several megabasepair can be present in the human genome without clinical consequence, how to visually circumvent these benign areas and provide laser-focused assessment of disease implications is not always appreciated by practitioners used only to highly costly molecular profiling methods (FISH / aCGH / NGS). Knowledge of the rare but recurrent rearrangements unfamiliar to practitioners saves time and money for molecular cytogeneticists and genetics counselors in helping to distinguish benign from harmful CG-CNV. It also supports them in further assessment of which molecular cytogenetics tools to deploy. Detailed discussion of how to define the inheritance and formation of cytogenetically visible copy number variations using cytogenetic and molecular approaches for genetic diagnostics, patient counseling and treatment plan development Uniquely classifies all known variants by chromosomal origin, cutting time and money for researchers in reviewing benign and pathologic variants before costly molecular methods are used to investigate Side-by-side comparison of copy number variants with their recently identified submicroscopic form, aiding technology assessment using aCGH and other techniques


Please wait while this item is added to your cart...