This book aims to develop engineering problem solving skills while incorporating a focused treatment of key life science concepts. Based on new material added to his own courses, the author discusses these concepts as they can be applied to the development and design of biomedical devices. The third edition of this text features updated information in each chapter that reflects the latest research on topics such as thermodynamics, cell membranes, body fluids, bioartificial organs, biological systems, extracorporeal devices, tissue engineering, pharmacokinetic analysis, and more. The text also includes new problems as well as additional examples.