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Basic and Clinical Endocrinology

by: Greenspan, Francis S.

Basic and Clinical Endocrinology

by: Greenspan, Francis S.

ISBN 13:
9780838505977
ISBN 10:
083850597X
Edition: 6th
Format: Paperback
Copyright: 11/16/2000
Publisher: Appleton
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Summary

Definitive, concise and current, this top-tier resource focuses on the pathophysiology, diagnosis, and treatment of endocrine disorders. The extensively revised sixth edition reflects the rapid progress made in understanding molecular mechanisms, in addition to improved techniques of diagnosis and therapy.

Authors

Preface

Introduction to Endocrinology

(37)

John D. Baxter

Ralff C. J. Ribeiro

The Endocrine System

(2)

Paracrine & Autocrine Actions

(1)

Chemical Composition of Hormones

(1)

Vitamins & Hormones

(1)

Hormones & Oncogenes

(1)

Hormones & the Immune System

(1)

Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds

(1)

Mechanisms of Hormone Action

(2)

Hormone Receptors

(1)

Regulation of Responsiveness to Hormones

(1)

Interactions Between Hormone Response Systems

(1)

Classes of Hormone Action

(3)

Use of Receptors for Classifying Types of Hormone Action

(1)

Classification of Hormones by the Types of Ligands: Agonists, Antagonists, Partial Agonists-Partial Antagonists, & Inactive Compounds

(1)

Endocrine & Nervous System Relationships: Neuroendocrinology

(2)

Neurotransmitters & Hormones

(1)

Hypothalamic-Pituitary Relationships

(2)

Gene Expression in Endocrinology & Metabolism: Molecular Basis for Function of the System & Genetic Endocrine Disease

(1)

Evolution of the Endocrine System

(3)

Cellular Control Networks & the Origins of Regulatory Chemicals

(1)

The Origins of Regulatory Proteins

(1)

The Origins of Hormones

(1)

Intracellular Communication

(1)

Evolution of Genes Involved in the Endocrine System

(1)

Integrative Networks

(1)

Evolution of the Endocrine Glands

(1)

Hormone Synthesis & Release

(1)

Hormone Transport

(2)

Steroid & Thyroid Hormones & Vitamin D

(1)

Polypeptide Hormones

(1)

Metabolism & Elimination of Hormones

(1)

Peptide Hormones

(1)

Steroid & Thyroid Hormones & Vitamin D

(1)

Catecholamine & Eicosanoid Metabolism

(1)

Regulation of the Endocrine System

(1)

Actions of Hormones

(3)

Developmental/Effects

(1)

Cell Growth & Cancer

(1)

Central Nervous System Effects

(1)

Effects on Metabolism

(1)

Effects on Cardiovascular & Renal Function

(1)

Effects on Mineral & Water Metabolism

(1)

Effects on Skeletal Functions

(1)

Effects on Reproductive Function

(1)

Release of Other Hormones

(1)

Effects on Immunologic Functions

(1)

Disorders of the Endocrine System

(4)

Endocrine Hypofunction

(1)

Endocrine Hyperfunction

(1)

Defects in Sensitivity to Hormones

(1)

Syndromes of Hormone Excess Due to Administration of Exogenous Hormone or Medication

(1)

Disorders of the Endocrine Glands not Associated With Endocrine Disease

(1)

Approach to the Patient With Endocrine Disease

(7)

History & Physical Examination

(1)

Laboratory Studies

(4)

Screening for Endocrine Diseases

(1)

Treatment of Endocrine Diseases

(1)

Uses of Hormones in Therapy of Nonendocrine Disease

(4)

Hormone Synthesis & Release

(21)

Vishwanath R. Lingappa

Synthia H. Mellon

Overview of Hormone Biosynthesis

(1)

Membrane Vesicle-Mediated Hormone Export

(10)

Hormone Export not Mediated by Membrane Vesicles

(6)

Metabolism, Transport, Elimination, & Regulation of Hormones

(4)

Mechanisms of Hormone Action

(21)

David G. Gardner

Receptors

(18)

Neurotransmitter & Peptide Hormone Receptors

(1)

Seven-Transmembrane Receptors

(1)

G Protein Transducers

(1)

Effectors

(3)

G Protein-Linked Receptors & Human Disease

(1)

Growth Factor Receptors

(2)

Cytokine Receptors

(1)

Guanylyl Cyclase-Linked Receptors

(1)

Nuclear Action of Peptide Hormones

(1)

Nuclear Receptors

(1)

Steroid Receptor Family

(2)

Thyroid Receptor Family

(3)

Nongenomic Effects of the Steroid Hormones

(1)

Steroid & Thyroid Hormone Receptor Resistance Syndromes

(3)

Endocrine Autoimmunity

(20)

Juan Carlos Jaume

Basic Immune Components & Mechanisms

(9)

Immune Recognition & Response

(4)

Tolerance

(5)

Autoimmunity Is Multifactorial

(1)

Genetic Factors in Autoimmunity

(1)

Environmental Factors in Autoimmunity

(1)

Single Gland Autoimmune Syndromes

(6)

Autoimmune Aspects of Thyroid Disease

(2)

Autoimmune Aspects of Type 1 Diabetes

(2)

Autoimmune Aspects of Other Endocrinopathies

(2)

Autoimmune Polyglandular Syndromes

(3)

Autoimmune Polyglandular Syndrome I (APS-I)

(1)

Autoimmune Polyglandular Syndrome II (APS-II)

(1)

Management of Autoimmune Polyglandular Syndromes

(2)

Hypothalamus & Pituitary

100

(63)

David C. Aron

James W. Findling

J. Blake Tyrrell

Hypothalamic Hormones

105

(5)

Anterior Pituitary Hormones

110

(9)

ACTH & Related Peptides

110

(2)

Growth Hormone

112

(2)

Prolactin

114

(2)

Thyrotropin

116

(1)

Gonadotropins: Luteinizing Hormone, Follicle-Stimulating Hormone

117

(2)

Endocrinologic Evaluation of the Hypothalamic-Pituitary Axis

119

(7)

Evaluation of ACTH

120

(1)

Evaluation of Growth Hormone

121

(1)

Evaluation of Prolactin

122

(1)

Evaluation of TSH

122

(1)

Evaluation of LH & FSH

122

(1)

Problems in Evaluation of the Hypothalamic-Pituitary Axis

122

(1)

Effects of Pharmacologic Agents on Hypothalamic-Pituitary Function

123

(1)

Endocrine Tests of Hypothalamic-Pituitary Function

123

(1)

Neuroradiologic Evaluation

123

(3)

Pituitary & Hypothalamic Disorders

126

(25)

Empty Sella Syndrome

128

(1)

Hypothalamic Dysfunction

129

(1)

Hypopituitarism

130

(6)

Pituitary Adenomas

136

(15)

Posterior Pituitary

151

(12)

Antidiuretic Hormone (ADH; Vasopressin)

151

(1)

Oxytocin

152

(1)

Control of Water Balance

152

(2)

Diabetes Insipidus

154

(4)

Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH)

158

(5)

Growth

163

(38)

Dennis Styne

Normal Growth

163

(15)

Intrauterine Growth

163

(1)

The Placenta

164

(1)

Classic Hormones of Growth & Fetal Growth

164

(1)

Growth Factors & Oncogenes in Fetal Growth

164

(1)

Insulin-like Growth Factors, Receptors, & Binding Proteins

164

(1)

Insulin

165

(1)

Epidermal Growth Factor

165

(1)

Fetal Origins of Adult Disease

166

(1)

Postnatal Growth

166

(10)

Measurement of Growth

176

(2)

Skeletal (Bone) Age

178

(1)

Disorders of Growth

178

(23)

Short Stature Due to Nonendocrine Causes

178

(6)

Short Stature Due to Endocrine Disorders

184

(11)

The Diagnosis of Short Stature

195

(1)

Tall Stature Due to Nonendocrine Causes

196

(1)

Tall Stature Due to Endocrine Disorders

197

(4)

The Thyroid Gland

201

(72)

Francis S. Greenspan

Anatomy & Histology

202

(2)

Physiology

204

(1)

Structure of Thyroid Hormones

204

(1)

Iodine Metabolism

204

(2)

Thyroid Hormone Synthesis & Secretion

206

(4)

Abnormalities in Thyroid Hormone Synthesis & Release

210

(1)

Thyroid Hormone Transport

210

(3)

Metabolism of Thyroid Hormones

213

(4)

Control of Thyroid Function

217

(5)

The Action of Thyroid Hormones

222

(3)

Physiologic Changes in Thyroid Function

225

(1)

Thyroid Autoimmunity

226

(1)

Tests of Thyroid Function

227

(1)

Tests of Thyroid Hormones in Blood

227

(1)

Evaluation of the Hypothalamic-Pituitary-Thyroid Axis

228

(1)

Iodine Metabolism & Biosynthetic Activity

229

(2)

Thyroid Imaging

231

(1)

Thyroid Ultrasonography or Magnetic Resonance Imaging

231

(1)

Thyroid Biopsy

232

(1)

Effects of Thyroid Hormones on Peripheral Tissues

232

(1)

Measurement of Thyroid Autoantibodies

232

(1)

Summary: Clinical Use of Thyroid Function Tests

233

(1)

Disorders of the Thyroid

233

(2)

Hypothyroidism

235

(7)

Hyperthyroidism & Thyrotoxicosis

242

(11)

Thyroid Hormone Resistance Syndromes

253

(1)

Nontoxic Goiter

254

(2)

Thyroiditis

256

(2)

Effects of Ionizing Radiation on the Thyroid Gland

258

(2)

Thyroid Nodules & Thyroid Cancer

260

(13)

Mineral Metabolism & Metabolic Bone Disease

273

(61)

Dolores Shoback

Robert Marcus

Daniel Bikle

Gordon Strewler

Cellular & Extracellular Calcium Metabolism

273

(1)

Parathyroid Hormone

274

(5)

Calcitonin

279

(2)

Vitamin D

281

(7)

Integrated Control of Mineral Homeostasis

288

(1)

Medullary Thyroid Carcinoma

288

(1)

Hypercalcemia

288

(12)

Hypocalcemia

300

(6)

Bone Anatomy & Remodeling

306

(4)

Osteoporosis

310

(10)

Osteomalacia & Rickets

320

(6)

Paget's Disease of Bone (Osteitis Deformans)

326

(3)

Renal Osteodystrophy

329

(5)

Glucocorticoids & Adrenal Androgens

334

(43)

David C. Aron

James W. Findling

J. Blake Tyrrell

Embryology & Anatomy

334

(3)

Biosynthesis of Cortisol & Adrenal Androgens

337

(5)

Circulation of Cortisol & Adrenal Androgens

342

(1)

Metabolism of Cortisol & Adrenal Androgens

342

(1)

Biologic Effects

343

(8)

Glucocorticoids

343

(4)

Adrenal Androgens

347

(1)

Laboratory Evaluation

347

(4)

Disorders of Adrenocortical Insufficiency

351

(9)

Primary Adrenocortical Insufficiency (Addison's Disease)

351

(4)

Secondary Adrenocortical Insufficiency

355

(1)

Diagnosis of Adrenocortical Insufficiency

355

(3)

Treatment of Adrenocortical Insufficiency

358

(2)

Prognosis of Adrenocortical Insufficiency

360

(1)

Cushing's Syndrome

360

(17)

Hirsutism & Virilism

371

(1)

Incidental Adrenal Mass

371

(2)

Glucocorticoid Therapy for Nonendocrine Disorders

373

(4)

Endocrine Hypertension

377

(22)

Burl R. Don

Morris Schambelan

Hypertension of Adrenal Origin

377

(12)

Hypertension of Renal Origin

389

(6)

Other Hormone Systems & Hypertension

395

(4)

Adrenal Medulla

399

(23)

Alan Goldfien

Anatomy

399

(1)

Hormones of the Adrenal Medulla

400

(10)

Catecholamines

400

(9)

Other Hormones

409

(1)

Disorders of Adrenal Medullary Function

410

(1)

Adrenal Medullary Hypofunction

410

(1)

Adrenal Medullary Hyperfunction

410

(1)

Pheochromocytoma

411

(11)

Testes

422

(31)

Glenn D. Braunstein

Anatomy & Structure-Function Relationships

422

(2)

Testes

422

(2)

Accessory Structures

424

(1)

Physiology of the Male Reproductive System

424

(4)

Gonadal Steroids

424

(2)

Control of Testicular Function

426

(2)

Evaluation of Male Gonadal Function

428

(3)

Clinical Evaluation

428

(1)

Laboratory Tests of Testicular Function

428

(3)

Pharmacology of Drugs Used to Treat Male Gonadal Disorders

431

(3)

Androgens

431

(2)

Gonadotropins

433

(1)

Gonadotropin-Releasing Hormone

434

(1)

Clinical Male Gonadal Disorders

434

(19)

Klinefelter's Syndrome

434

(2)

Bilateral Anorchia

436

(1)

Leydig Cell Aplasia

437

(1)

Cryptorchidism

437

(2)

Noonan's Syndrome (Male Turner's Syndrome)

439

(1)

Myotonic Dystrophy

440

(1)

Adult Seminiferous Tubule Failure

440

(1)

Adult Leydig Cell Failure (Andropause)

441

(1)

Erectile Dysfunction (Impotence)

442

(2)

Male Infertility

444

(2)

Gynecomastia

446

(2)

Testicular Tumors

448

(5)

Ovaries

453

(56)

Alan Goldfien

Anatomy of the Ovaries

453

(1)

Hormones of the Ovary

454

(6)

Steroid Hormones

454

(6)

Relaxin

460

(1)

Other Ovarian Hormones & Regulatory Substances

460

(1)

The Menstrual Cycle

461

(6)

Hormonal Profiles During the Menstrual Cycle

461

(2)

The Ovarian Cycle

463

(3)

Hormone Interaction & Regulation During the Menstrual Cycle

466

(1)

Cyclic Changes in the Female Reproductive Tract

467

(4)

Histology of the Endometrium Throughout the Menstrual Cycle

467

(2)

Cervical Mucus

469

(1)

Vaginal Epithelium

470

(1)

Extragenital Symptoms Associated With Normal Menstrual Function

471

(2)

Premenstrual Dysmorphic Disorder (Premenstrual Syndrome)

471

(1)

Dysmenorrhea

472

(1)

Disorders of Ovarian & Menstrual Function

473

(15)

Amenorrhea in the Absence of Sexual Maturation

474

(1)

Amenorrhea in Patients With Normal Secondary Sex Characteristics

474

(6)

Disorders of Androgen Metabolism

480

(3)

Hirsutism

483

(5)

Anovulatory Bleeding

488

(1)

Ovulation Induction

488

(2)

Clomiphen Citrate

488

(1)

Human Menopausal Gonadotropins (Menotropins)

489

(1)

Gonadotropin-Releasing Hormone

490

(1)

Bromocriptine

490

(1)

Therapeutic Use of Ovarian Hormones & Their Synthetic Analogs

490

(1)

Treatment of Primary Hypogonadism

490

(1)

Ovarian Suppression

490

(1)

Threatened Abortion

490

(1)

Inadequate Luteal Phase

491

(1)

Diagnostic Uses

491

(1)

Inhibitors of Ovarian Function

491

(2)

Gonadotropin-Releasing Hormone Analogs & Antagonists

491

(1)

Selective Estrogen Receptor Modulators & Antiestrogens

491

(1)

Danazol

492

(1)

Antiprogestins

492

(1)

Antiandrogens

492

(1)

Menopause

493

(5)

Hormonal Changes

493

(1)

Clinical Manifestations of Menopause

494

(1)

Management of Menopause

495

(3)

Hormonal Contraception (Oral Contraceptives)

498

(5)

Pharmacologic Effects of Estrogens & Synthetic Progestins

498

(1)

Clinical Uses of Oral Contraceptives

499

(1)

Adverse Effects of Oral Contraceptives

500

(2)

Noncontraceptive Advantages of Hormonal Contraception

502

(1)

Contraindications & Cautions

502

(1)

Drug Interactions With Oral Contraceptives

502

(1)

Contraception With Progestins

503

(1)

Postcoital Contraceptives & Emergency Contraception

503

(1)

Infertility

503

(6)

Semen Abnormalities

503

(1)

Ovulatory Disorders

504

(1)

Infertility in the Presence of Ovulation

504

(1)

In Vitro Fertilization

505

(1)

Gamete Intrafollicular Transfer (GIFT)

505

(4)

Abnormalities of Sexual Determination & Differentiation

509

(38)

Felix A. Conte

Melvin M. Grumbach

Normal Sex Differentiation

509

(6)

Testicular & Ovarian Differentiation

515

(2)

Psychosexual Differentiation

517

(2)

Abnormal Sex Differentiation

519

(1)

Seminiferous Tubule Dysgenesis: Chromatin-Positive Klinefelter's Syndrome & Its Variants

520

(2)

Syndrome of Gonadal Dysgenesis: Turner's Syndrome & Its Variants

522

(2)

46, XX & 46, XY Gonadal Dysgenesis

524

(2)

True Hermaphroditism

526

(1)

Female Pseudohermaphroditism

527

(4)

P450 Aromatase Deficiency

531

(1)

Maternal Androgens & Progestogens

531

(1)

Male Pseudohermaphroditism

531

(12)

Unclassified Forms of Abnormal Sexual Development in Males

543

Unclassified Forms of Abnormal Sexual Development in Females

542

(1)

Management of Patients With Intersex Problems

542

(5)

Puberty

547

(28)

Dennis Styne

Physiology of Puberty

547

(9)

Delayed Puberty or Absent Puberty (Sexual Infantilism)

556

(10)

Precocious Puberty (Sexual Precocity)

566

(9)

The Endocrinology of Pregnancy

575

(28)

Robert N. Taylor

Dan I. Lebovic

Mary C. Martin-Cadieux

Conception & Implantation

575

(1)

Fetal-Placental-Decidual Unit

576

(1)

Polypeptide Hormones

577

(3)

Steroid Hormones

580

(1)

Maternal Adaptation to Pregnancy

581

(3)

Fetal Endocrinology

584

(2)

Endocrine Control of Parturition

586

(1)

Endocrinology of the Puerperium

587

(2)

Endocrine Disorders & Pregnancy

589

(14)

Pregnancy & Pituitary Pathology

589

(1)

Pregnancy & Breast Cancer

590

(1)

Hypertensive Disorders of Pregnancy

591

(1)

Hyperthyroidism in Pregnancy

592

(1)

Hypothyroidism in Pregnancy

593

(1)

Diabets Mellitus & Pregnancy

593

(10)

John L. Kitzmiller

Regulatory Peptides of the Gut

603

(20)

Sean J. Mulvihill

Haile T. Debas

Gastrin

607

(1)

Cholecystokinin

608

(1)

Secretin

609

(1)

Somatostatin

609

(1)

Bombesin & Gastrin-Releasing Peptide

610

(1)

Calcitonin Gene-Related Peptide

611

(1)

Gastric Inhibitory Peptide

611

(1)

Vasoactive Intestinal Peptide

611

(1)

Galanin

612

(1)

Substance P

612

(1)

Enkephalins

612

(1)

Neurotensin

613

(1)

Motilin

613

(1)

Pancreatic Polypeptide Family

614

(1)

Enteroglucagon

614

(1)

Abnormalities of Regulatory Peptides in Diseases of the Gastrointestinal Tract

614

(5)

Duodenal Ulcer

614

(1)

Motility Disorders of the Gastrointestinal Tract

615

(1)

Inflammatory Bowel Disease

615

(1)

Neuroendocrine Tumors of the Gut

616

(1)

Multiple Endocrine Neoplasia Syndromes

616

(1)

Zollinger-Ellison Syndrome

616

(1)

VIPoma

617

(1)

Glucagonoma

617

(1)

Carcinoid Tumors & Carcinoid Syndrome

617

(1)

Miscellaneous Tumors

618

(1)

Minimally Invasive Approaches to Gut Endocrine Tumors

619

(1)

Clinical Uses of Gut Peptides

619

(4)

Pancreatic Hormones & Diabetes Mellitus

623

(76)

Umesh Masharani

John H. Karam

The Endocrine Pancreas

623

(10)

Anatomy & Histology

623

(1)

Hormones of the Endocrine Pancreas

624

(9)

Diabetes Mellitus

633

(8)

Classification

633

(1)

Type 1 Diabetes Mellitus

633

(3)

Type 2 Diabetes

636

(2)

Other Specific Types of Diabetes

638

(3)

Clinical Features of Diabetes Mellitus

641

(2)

Type 1 Diabetes

641

(1)

Type 2 Diabetes

642

(1)

Laboratory Findings in Diabetes Mellitus

643

(4)

Urinalysis

643

(1)

Blood Glucose Testing

644

(1)

Serum Ketone Determinations

645

(1)

Glycosylated Hemoglobin Assays

645

(1)

Capillary Morphometry

646

(1)

Lipoproteins in Diabetes

646

(1)

Diagnosis of Diabetes Mellitus

647

(1)

Oral Glucose Tolerance Test

647

(1)

Insulin Levels

648

(1)

Intravenous Glucose Tolerance Test

648

(1)

Treatment of Diabetes Mellitus

648

(27)

Diet

651

(2)

Oral Agents for the Treatment of Hyperglycemia

653

(8)

Insulin

661

(5)

Steps in the Management of the Diabetic Patient

666

(9)

Acute Complications of Diabetes Mellitus

675

(11)

Hypoglycemia

675

(3)

Coma

678

(8)

Chronic Complications of Diabetes Mellitus

686

(8)

Specific Chronic Complications of Diabetes Mellitus

688

(6)

Surgery in the Diabetic Patient

694

(1)

Diabetics Regulated by Diet Alone

694

(1)

Diabetics Taking Oral Hypoglycemic Agents

694

(1)

Diabetics Taking Insulin

694

(1)

Prognosis for Patients With Diabetes Mellitus

695

(4)

Hypoglycemic Disorders

699

(17)

John H. Karam

Pathophysiology of the Counterregulatory Response to Neuroglycopenia

699

(4)

Classification of Hypoglycemic Disorders

703

(1)

Clinical Presentation of Hypoglycemia

704

(2)

Specific Hypoglycemic Disorders

706

(10)

Symptomatic Fasting Hypoglycemia With Hyperinsulinism

706

(6)

Symptomatic Fasting Hypoglycemia Without Hyperinsulinism

712

(1)

Nonfasting Hypoglycemia (Reactive Hypoglycemia)

713

(3)

Disorders of Lipoprotein Metabolism

716

(29)

Mary J. Malloy

John P. Kane

Atherosclerosis

716

(1)

Overview of Lipid Transport

717

(5)

Differentiation of Disorders of Lipoprotein Metabolism

722

(2)

Clinical Descriptions of Primary & Secondary Disorders of Lipoprotein Metabolism

724

(8)

The Hypertriglyceridemias

724

(1)

Primary Hypertriglyceridemia

725

(2)

Secondary Hypertriglyceridemia

727

(4)

The Primary Hypercholesterolemias

731

(1)

Familial Hypercholesterolemia

731

(1)

Familial Combined Hyperlipidemia

732

(1)

LP(a) Hyperlipoproteinemia

732

(1)

Familial Ligand-Defective Apo B

732

(1)

Secondary Hypercholesterolemia

732

(1)

Hypothyroidism

732

(1)

Nephrosis

733

(1)

Immunoglobulin Disorders

733

(1)

Anorexia Nervosa

733

(1)

Cholestasis

733

(1)

The Primary Hypolipidemias

733

(4)

Primary Hypolipidemia Due to Deficiency of High-Density Lipoproteins

734

(1)

Primary Hypolipidemia Due to Deficiency of Apo B-Containing Lipoproteins

735

(1)

Secondary Hypolipidemia

736

(1)

Other Disorders of Lipoprotein Metabolism

736

(1)

The Lipodystrophies

736

(1)

Rare Disorders

737

(1)

Treatment of Hyperlipidemia

737

(8)

Dietary Factors in the Management of Lipoprotein Disorders

738

(1)

Drugs Used in Treatment of Hyperlipoproteinemia

739

(1)

Bile Acid Sequestrants

739

(1)

Niacin (Nicotinic Acid)

740

(1)

Fibric Acid Derivatives

741

(1)

HMG-CoA Reductase Inhibitors

741

(1)

Combined Drug Therapy

742

(1)

Possible Untoward Consequences of Lipid-Lowering Therapy

743

(2)

Obesity & Overweight

745

(17)

Marc K. Hellerstein

Elizabeth J. Parks

Controversies & Uncertainties Regarding the Pathogenesis of Obesity

754

(1)

Survey of Treatment Approaches & Their Efficacy

755

(4)

Dietary Therapies

755

(1)

Surgical Treatment of Obesity

756

(1)

Pharmacologic Therapies

756

(3)

Other Conditions Affected by Treatment of Obesity or Overweight

759

(1)

Type 2 Diabetes Mellitus

759

(1)

Hyperlipidemia

759

(1)

Polycystic Ovarian Syndrome

759

(1)

Hypertension

759

(1)

Gallstones

759

(1)

Osteoarthritis & Other Weight-Sensitive States

759

(1)

A Systematic Approach to the Treatment of Obesity

759

(3)

Hormones & Cancer

762

(16)

Debasish Tripathy

Christopher C. Benz

Hormonal Effects on Tumors

762

(3)

Growth Promotion & Malignant Transformation

762

(2)

Tumor Growth Mediated by Autocrine & Paracrine Factors

764

(1)

Steroid-Dependent Tumors

765

(1)

Tumors Affecting Endocrine Status

765

(2)

Nonsecretory Tumors

765

(1)

Secretory Tumors

765

(1)

Treatment-Induced Endocrinopathy

766

(1)

Endocrine Therapy for Cancer

767

(3)

Steroid Receptors & Treatment

767

(1)

Primary Modalities of Endocrine Intervention

768

(1)

Combination Endocrine Therapy

769

(1)

Chemo-Endocrine Therapy

770

(1)

Clinical Problems

770

(8)

Breast Cancer in Women

770

(4)

Breast Cancer in Men

774

(1)

Endometrial Cancer

774

(1)

Prostatic Cancer

775

(1)

Miscellaneous Tumors

776

(2)

Humoral Manifestations of Malignancy

778

(14)

Dolores Shoback

Janet Funk

Ectopic Hormone & Receptor Syndromes

778

(1)

Hypercalcemia of Malignancy

779

(4)

Ectopic Cushing's Syndrome

783

(2)

Syndrome of Inappropriate ADH (SIADH) Secretion

785

(1)

Non-Islet Cell Tumors & Hypoglycemia

786

(1)

Other Hormones Secreted by Tumors

787

(1)

Oncogenic Osteomalacia

788

(1)

Gut Hormones

789

(1)

Erythropoietin

789

(1)

Renin

789

(3)

Multiple Endocrine Neoplasia

792

(10)

David G. Gardner

Multiple Endocrine Neoplasia Type 1 (MEN 1)

792

(5)

Multiple Endocrine Neoplasia Type 2 (MEN 2)

797

(5)

Geriatric Endocrinology

802

(21)

Susan L. Greenspan

Neil M. Resnick

Thyroid Function & Disease

802

(3)

Disorders of the Thyroid Gland

803

(2)

Carbohydrate Intolerance & Diabetes Mellitus

805

(3)

Aging & the Physiology of Carbohydrate Intolerance

805

(1)

Diabetes Mellitus

806

(2)

Nonketotic Hyperosmolar Coma

808

(1)

Osteoporosis & Calcium Homeostasis

808

(8)

Osteoporosis

808

(7)

Hyperparathyroidism

815

(1)

Changes in Water Balance

816

(1)

Hypernatremia

816

(1)

Hyponatremia

816

(1)

Hyporeninemic Hypoaldosteronism

816

(1)

Glucocorticoids & Stress

817

(1)

Disorders of the Hypothalamic-Pituitary-Adrenal Axis

817

(1)

Changes in Reproductive Function in Men

818

(1)

Benign Prostatic Hyperplasia

819

(4)

Endocrine Emergencies

823

(23)

David G. Gardner

Francis S. Greenspan

Myxedema Coma

823

(1)

Thyroid Storm

824

(1)

Thyrotoxic Periodic Paralysis

825

(1)

Amiodarone Induced Thyrotoxicosis

826

(1)

Acute Adrenal Insufficiency

827

(1)

Pituitary Apoplexy

828

(1)

Diabetic Ketoacidosis

829

(3)

Nonketotic Hyperosmolar Coma

832

(3)

Hypercalcemic Crisis

835

(2)

Acute Hypocalcemia

837

(2)

Hyponatremia

839

(2)

Diabetes Insipidus

841

(5)

AIDS Endocrinopathies

846

(7)

Deborah E. Sellmeyer

Carl Grunfeld

Thyroid Disorders

846

(1)

Adrenal Disorders

847

(2)

Bone & Mineral Disorders

849

(1)

Gonadal Disorders

849

(1)

Pituitary Disorders

850

(1)

Pancreatic Disorders

850

(1)

Lipid Disorders

851

(1)

Conclusion

851

(2)

Appendix: Table of Normal Hormone Reference Ranges

853

(14)

Index

867

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Basic and Clinical Endocrinology

Basic and Clinical Endocrinology

9780838505977

083850597X

Summary

Table of Contents

Supplemental Materials

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Amazon no longer offers textbook rentals. We do!

Basic and Clinical Endocrinology

Basic and Clinical Endocrinology

9780838505977

083850597X

Summary

Table of Contents

Supplemental Materials

Write a Review

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