Atherosclerosis : Molecular and Cellular Mechanisms
ISBN: 9783527324484 | 3527324488
Edition: 1stFormat: Hardcover
Publisher: Wiley-Blackwell
Pub. Date: 4/5/2010
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western world, this handbook and ready reference provides a comprehensive account of the different stages and factors in the development of the atherosclerotic plaque. Each chapter is written by experts in the field and highlights the role of specific mediators of atherosclerotic plaque development, as well as potential therapeutic targets. A large amount of this up-to-date information is conveyed by way of tables and schematic figures, in a readily comprehensible manner. A must-have for master and PhD students, researchers, MDs and lecturers i... MORE
| Introduction | |
| Pathogenesis Of Atherosclerosis | |
| Proinflammatory Factors | |
| Chemokines And Atherosclerosis: A Critical Assessment Of Therapeutic Targets | |
| Adhesion Molecules And Atherosclerosis | |
| Cytokines And Atherosclerosis | |
| Toll-Like Receptors In Atherosclerosis | |
| Ppar-Based Therapies For The Management Of Atherosclerosis | |
| Pentraxins In ... MORE | |
| Proteases | |
| Metalloproteinases, The Endothelium And Atherosclerosis | |
| Cathepsins In Atherosclerosis | |
| The Plasmin System And Atherosclerosis | |
| Mast Cell Proteases And Atherosclerosis | |
| Hyperlipidemia | |
| Macrophage Foam Cell Formation: The Pathways To Cholesterol Engorgement | |
| Oxidative Stress | |
| Nadph Oxidase And Atherosclerosis | |
| Uncoupling Of Endothelial Nitric Oxide Synthase In Atherosclerosis | |
| Heme Oxygenase-1 And Atherosclerosis | |
| Cell Growth And Phenotype | |
| Phenotypic Heterogeneity Of Smooth Muscle Cells. Implications For Atherosclerosis | |
| Platelets: Their Role In Atherogenesis And Thrombosis In Coronary Artery Disease | |
| Bosis In Coronary Artery Disease | |
| Modulators Of Monocyte And Macrophage Phenotypes In Atherosclerosis | |
| Table of Contents provided by Publisher. All Rights Reserved. |
Sarah George is a Reader in the Bristol Heart Institute at the University of Bristol. After obtaining her undergraduate and post-doctoral degree at the University of Cardiff she moved to the University of Bristol. Her research interests are the regulation of smooth muscle cell behaviour in atherosclerosis and restenosis, most recent studies have focused on the role of cell-cell contacts and the Wnt pathway. Dr George has written over 50 scientific original articles and was awarded the British Atherosclerosis Society John French Lecture in 2005.
Jason Johnson is a British Heart Foundation Intermediate Research Fellow at the University of Bristol. He undertook both his Masters and Doctorate at the University of Bristol in the Bristol Heart Institute. His research interests are the role of matrix metalloproteinases in atherosclerosis and restenosis. He also contributed to the establishment of the first spontaneous mouse model of atherosclerotic plaque rupture. Dr Johnson was awarded the British Atherosclerosis Society Young Investigator Award
Jason Johnson is a British Heart Foundation Intermediate Research Fellow at the University of Bristol. He undertook both his Masters and Doctorate at the University of Bristol in the Bristol Heart Institute. His research interests are the role of matrix metalloproteinases in atherosclerosis and restenosis. He also contributed to the establishment of the first spontaneous mouse model of atherosclerotic plaque rupture. Dr Johnson was awarded the British Atherosclerosis Society Young Investigator Award
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