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Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition

ISBN: 9780071603935 | 007160393X
Edition: 6th
Format: Hardcover
Publisher: McGraw-Hill Medical
Pub. Date: 4/11/2012

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SummaryTable of Contents
A complete, up-to-date text on the practical application of biopharmaceuticals and pharmacokinetics Applied Biopharmaceutics & Pharmacokineticsis written to provide you with a basic understanding of the principles of biopharmaceutics and pharmacokinetics as applied to drug product development and drug therapy. The revised and updated sixth edition remains unique in teaching basic concepts that may be applied to understanding complex issues associated with in vivo drug delivery that are essential for safe and effective drug therapy. The text int... MORE

Preface

Glossary

1. Intrtoduction to Biopharmaceutics and Pharmacokinetics

2. Mathematical Fundamentals in Pharmacokinetics

3. One-compartment Open Model: Intravenous Bolus Administration 5. Intravenous Infusion

6. Drug Elimination and clearance

7. Pharmacokinetics of Oral Absorption

8. Multiple-Dosage Regimens

9. Monlinear Pharmacokinetics

10. Physiologic Drub Distribution and Protein Binding

11. Drug Elimination and Hepatic Clearance

12. Ph... MORE

13. Physioloic Factors Related to Drug Absorption

14. Biopharmaceutc Consideratins in Drug Product Desitgn and In Vitro Drug Product Performance

15. Drug Product Performance, In Vivo: Bioavailability and Bioequivalence

16. Impact of Drug Product Quality and Biopharmaceutics on Clincal Efficacy

17. Modified-Release Drug Products

18. Targeted Drug Delivery Symptoms and Biotechnological Products

19. Relationship Between Pharmacokeinetics and Pharmacodynamics

20. Application of Pharmacokinetics to Clinical Situations

21. Dose Adjustment in Renal and Hepatic Disease Appendix A Statistics

Appendix B Applications of Computer in Pharmacokinetcs

Appendix C Solutions to Frequently Asked Questions (FAQs) and Learning Questions

Appendix D Guiding Prinicples for Human and Animal Research

Appendix E Popular Drugs and Pharmacokinetic Parameters

Index

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